Recent in Testing (page 13 of 21)

C + K Introduces Tewameter with Three Probes for Better Efficiency

Courage + Khazaka has upgraded its well-known TEWL and barrier function measurement device, the Tewameter, with three probe heads for better efficiency.

Measuring and Pre-selecting Functional Filler Pigments

Functional filler pigments play an important role in adjusting optical properties such as transparency and soft focus effects in cosmetics. However, their suitability for specific formulas is not apparent until time-consuming tests using many different fillers have been conducted. Therefore, a new method to predetermine the soft focus effects of functional filler pigments is described here.

In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics

Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.

Using Ultrasound Scanning to Characterize Colloidal Particles

Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

Solar Flair

If like me, you’re just daydreaming of the beach, this collection of articles will enlighten you with its focus on sun protection, SPF testing, damage repair and more.

A Synthetic Tissue-based In vitro Ocular Irritation Assay

The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.

Screening Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

Image Processing and Analysis to Evaluate the Effects of Porous Polyamide Microspheres in Cosmetics

Described here is an image processing system that compensates for changes in illumination and volunteer position, and two algorithms to quantify skin texture and wrinkles. These methods evaluate skin parameters from a single image without contacting skin. Their abilities are demonstrated here in evaluations of the benefits of porous polyamide ultra-fine powders on skin texture and gloss.

In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

Testing SPF 15–100, Indoor vs. Outdoor

Lab tests on sunscreens show it takes more energy to produce mild erythema on protected skin than unprotected skin. Yet the FDA questions the need for SPFs higher than 50. In response, two outdoor studies were conducted using commercial products to challenge standing premises and determine if there is a measurable difference in an SPF 100 and SPFs of 50 or less.

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