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Recent in Testing (page 12 of 32)
Jul 23, 2013
Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.
Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures
Jul 17, 2013
In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.
Jul 15, 2013
Although cellulite is not considered a disease, it is a significant cosmetic problem for many post-adolescent women. Recent studies using new diagnostic techniques such as ultrasound imaging can define the cellulite-reducing efficacy of cosmetics. However, there is still a need to standardize and objectify the testing procedures and to find parameters to measure anti-cellulite efficacy.
Jul 12, 2013
Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.
Jul 12, 2013
Nowadays, however, personal care has evolved even further to encompass the root of human being-ethics and morals, where the purchase of a personal care item relates to one’s concern about the environment and animal welfare. But the involvement of ethics does not just apply to the consumers using the products; it applies to scientists conducting safety studies.
Jul 10, 2013
It remains the responsibility of the manufacturer to substantiate the safety of both ingredients and finished cosmetic products prior to their being marketed.
Jul 10, 2013
In 2001, Japanese researchers reported that after the age of 40, some individuals develop a malodor known as “aging odor,” attributed to the presence of unsaturated C9, 2-nonenal. George Preti, PhD, a member of Monell Chemical Senses Center and an adjunct professor of dermatology at the University of Pennsylvania School of Medicine, was interested by this report and began to conduct research of his own.
Jul 1, 2013 | Sébastien Miksa, Dominique Lutz and Céline Guy, HelioScreen Labs
This work evaluates the impact of temperature on test substrate surfaces during the application, spreading and drying steps of the in vitro method to measure ultraviolet (UV) transmission. The authors work in a range between 20°C and 35°C, and demonstrate that controlling temperature is a key test parameter that should be strictly controlled to ensure reliability.
Jun 25, 2013
This study describes methods used in a Korean study to calculate consumer exposure to lipstick and face creams. The average amount applied daily was estimated and compared with data collected by weighing containers before and after use. The data collected was 1.8 to 1.6 times greater than the estimate, so although the survey represented real use patterns, the actual data was more accurate.
Jun 25, 2013
Particulate contamination and discoloration may occur in products due to foreign materials introduced via raw materials or during the manufacturing process. Agglomeration or reactions between ingredients and packaging components also are possible sources. The identification of contaminants and their origin, described here, is therefore critical so that future incidents can be prevented and safety or regulatory concerns can be addressed.
Jun 20, 2013
The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.
Jun 19, 2013
To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.
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Between The Covers Discover:
- Amino acid distribution and biochemistry
- Examination of strength and anti-breakage product claims
- Hair: growth cycle, heat protection, shine, and color intensity and retention
- Overview of shampoos and issues relating to surfactants
- Science of hair color including chemical reactions and formulations
- Ethnic differences in hair and absorption of materials
- Evaluate and quantify visual properties of hair
- Dandruff-Causes and biology of the condition
- Hair styling products and polymers
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Finally! This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns; and much more.Order your copy today.