Recent in Testing (page 11 of 20)

In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

In Vitro UV Testing—Robot vs. Human Spreading for Repeatable, Reproducible Results

Repeatability and reproducibility are crucial to validate any test method. In order to master these criteria, the authors developed an automated spreading device and compared it with human spreading. Application of the device in eight laboratories and using 36 sunscreens revealed great improvements via automated spreading, ensuring good intra- and inter-laboratory variability.

The Effect of Glycerol on the Water-holding Capacity of Chemically Irritated Skin*

Glycerol is one humectant commonly employed due to its high hygroscopic and hyperosmotic properties. It is used in cosmetics as a moisturizer and in pharmaceutical formulations as an active compound. Being naturally present in the skin, glycerol was quickly identified for its role in skin hydration, similar to natural moisturizing factors (NMF).

Solar Flair

If like me, you’re just daydreaming of the beach, this collection of articles will enlighten you with its focus on sun protection, SPF testing, damage repair and more.

A Synthetic Tissue-based In vitro Ocular Irritation Assay

The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.

Screening Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

Image Processing and Analysis to Evaluate the Effects of Porous Polyamide Microspheres in Cosmetics

Described here is an image processing system that compensates for changes in illumination and volunteer position, and two algorithms to quantify skin texture and wrinkles. These methods evaluate skin parameters from a single image without contacting skin. Their abilities are demonstrated here in evaluations of the benefits of porous polyamide ultra-fine powders on skin texture and gloss.

In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

Testing SPF 15–100, Indoor vs. Outdoor

Lab tests on sunscreens show it takes more energy to produce mild erythema on protected skin than unprotected skin. Yet the FDA questions the need for SPFs higher than 50. In response, two outdoor studies were conducted using commercial products to challenge standing premises and determine if there is a measurable difference in an SPF 100 and SPFs of 50 or less.

Testing Sun Protection Factor in Skin

There are various test methods set by global governing bodies for SPF protection, but this article will discuss the five time-point internationally approved ISO 24444 method.

Solar Flair

If like me, you’re just daydreaming of the beach, this collection of articles will enlighten you with its focus on sun protection, SPF testing, damage repair and more.

Image Processing and Analysis to Evaluate the Effects of Porous Polyamide Microspheres in Cosmetics

Described here is an image processing system that compensates for changes in illumination and volunteer position, and two algorithms to quantify skin texture and wrinkles. These methods evaluate skin parameters from a single image without contacting skin. Their abilities are demonstrated here in evaluations of the benefits of porous polyamide ultra-fine powders on skin texture and gloss.

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