Delivery with Chitosan-coated Liposomes and Other Topics: Literature Findings

Mar 1, 2009 | Contact Author | By: Charles Fox, Independent Consultant
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Title: Delivery with Chitosan-coated Liposomes and Other Topics: Literature Findings
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Keywords: patents

Abstract: This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development including the chitosan-coated liposome delivery of tamarind, luminescent pigments, microemulsions and laudanosine for antiaging, among others.

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This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development including the chitosan-coated liposome delivery of tamarind, luminescent pigments, microemulsions and laudanosine for antiaging, among others.

Skin and Skin Care 
Skin moisturization: Tomaru has published a review on moisturizing products for the skin.1Moisturization is an important claim for skin care products. The stratum corneum (SC) has its own water-holding mechanisms but they are not always enough. Successful ways to moisturize skin include humectants and emollients that are adapted to the skin’s condition and the natural water-holding mechanisms.

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Footnotes

aRice Powder Extract No. 11 (INCI: Water (aqua) (and) Oryza Sativa (Rice) Extract) is a product of Yushin Syuzo.

bDynasylan MTES (INCI: Methyltriethoxysilane) and Dynasylan TEOS UHP (INCI: Tetraethyl Orthosilicate (and) Tetraethoxysilane) are products of Evonik Degussa GmbH.

cPolyphenon 70A is a flavonoid produced by Funakoshi Co., Ltd.

dAmphitol 20N (INCI: Lauramine Oxide) and Sanisol C (INCI: Alkylbenzyl Dimethyl Ammonium Chloride) are products of Kao Corp.

eSunsoft 750 (INCI: Glyceryl Laurate) is a product of Taiyo Kagasku.

fHaimalate PAM is a product of Kokyu Alcohol.

gHardness was evaluated using a Shimadzu EZ-Test-20N, a product of Shimadzu Corp.

Formula 1. W/O moisturizing day cream2

Glycerol 5.00% w/w
Ammonium polyacryldimethyltauramide (Hostacerin AMPS, Clariant) 1.00
Dimethicone/PEG-10/15 crosspolymer (and) dimethicone (KSG-210, Shin-Etsu)  4.00
Stearyl acrylate homopolymer 1.00
Isohexadecane 5.00
Cyclohexamethicone 3.00
Hydrogenated polyisobutene 7.00
Preservative  0.40
Water (aqua)  qs to 100.00

Formula 2. Antiaging cosmetic3

Carbopol (Ultrez-10, Noveon) 0.100% w/w
Glycerin 8.000
Steareth-2 (Volpo S2, Croda) 0.600
Cetearyl alcohol (and) dicetyl phosphate (and) ceteth-10 phosphate (Crodafos CES, Croda) 4.000
Cyclopentasiloxane (and) cyclohexasiloxane (DC-345, Dow Corning) 2.000
Caprylic/capric triglyceride (Crodamol GTCC, Croda) 10.000
Methylparaben 0.300
Sorbitan stearate (Crill-3, Croda) 1.600
Sodium sorbate 0.100
Teprenone (and) caprylic/capric triglyceride 1.000
Laudanosine (N-methyltetrahydropapaverine) 0.019
Sodium hydroxide, 30% 0.350
Fragrance (parfum) 0.100
 Water (aqua) qs to 100.000

Formula 3. Self-adhesive gel skin mask4

Sodium polyacrylate 1.20% w/w
PEG-40 stearate 0.50
Chondrus crispus (carrageenan) 1.25
Vinylpyrrolidone-vinylacetate copolymer 1.00
Acrylates/C10-C30 alkyl acrylate crosspolymer 1.50
Water-soluble dye  0.01
Cyclomethicone 1.00
Dimethiconol 0.50
Hydrogenated polyisobutene 0.50
Carnitine  0.50
Panthenol 0.50
Glycerin 3.00
Fragrance (parfum) qs
Methylpropanediol  4.50
Propylparaben 0.30
Water (aqua) qs to 100.00

Formula 4. Hair styling gel5

Acrylates/hydroxyesters acrylates copolymer (Acudyne 180, Rohm and Haas) 1.50% w/w
Acrylates/steareth-20 methacrylate crosspolymer 1.50
Poloxamer 231 (Pluronic L-81, BASF) 0.15
PEG/PPG-20/20 dimethicone (Abil B 8863, Degussa Care) 0.15
DMDM hydantoin 0.20
Fragrance (parfum) 0.20
PEG-40 hydrogenated castor oil 0.40
Water (aqua) qs to 100.00

Formula 5. Oily nonsticky lipstick6

Euphorbia cerifera (candelilla) wax 9.00% w/w
Copernicia cerifera (carnauba) wax 2.00
Paraffin 7.00
Hydrogenated castor oil dimer dilinoleate 25.00
Di(phytosteryl/octyldodecyl) N-lauroyl-l-glutamate 15.00
Caprylyl glycol 1.00
Pigment qs
Ricinus communis (castor) seed oil qs to 100.00

   

Formula 6. Nail growth treatment8

Water (aqua) 13.00% w/w
Ethanol 73.00
Ciclopirox 8.00
Ethyl acetate 4.00
Hydroxypropyl chitosan 1.00
Cetearyl alcohol 1.00
  100.00

Formula 7. O/W sunscreen lotion12

Glyceryl stearate citrate 1.50% w/w
Cetearyl alcohol 2.00
Acrylic acid/vinylpyrrolidone copolymer 0.50
Butylene glycol dicaprylate/dicaprate 10.00
Octyldodecanol 3.00
Myristyl myristate 1.00
Glycerin 2.00
Butyl methoxydibenzoylmethane 2.50
Ethylhexyl salicylate 4.00
Phenylbenzylimidazole sulfonic acid 3.00
Sodium starch octenylsuccinate 3.00
Ethanol 0.50
Taurine 0.10
Folic acid  0.01
Tocopheryl acetate 0.20
Disodium EDTA 0.10
Fragrance (parfum) qs
Preservative qs
Pigment qs
Sodium hydroxide qs
Water (aqua) qs to 100.00

Formula 8. Lipid microemulsion14

Water (aqua) 31.68% w/w
Sucrose 19.09
Glycerin 12.91
Polyglyceryl-10 polyricinoleate 4.51
Ethoxylated monodiglycerides (Mazol 80 MG, BASF) 18.23
Sterol esters 13.58
  100.00

Formula 9. Transparent lipstick18

Oil gelling agent 45.00% w/w
Polyglyceryl-2 diisostearate 22.50
Isotridecyl isononanoate 22.50
Copolymer of polyglyceryl-2 isostearate (and) a dimer of dilinoleic acids 5.00
Pentaerythritol triisostearate 5.00
  100.00

Formula 10. Hair styling treatment18

Oil gelling agent 10.00% w/w
Ethylhexyl hydroxystearate 5.00
Copolymer of polyglyceryl-2 isostearate (and) dimer dilinoleic acid 4.50
Pentylene glycol 3.00
Behenyl alcohol 2.50
Dodecylhexadecanol 2.00
Glyceryl stearate 2.00
 Dimethicone  2.00
Polyglyceryl-10 isostearate 1.50
Carbomer 0.60
Potassium hydroxide 0.162
Water (aqua) qs to 100.00

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