Stable O/W Nanoemulsions for Skin and Other Topics: Literature Findings

Mar 1, 2010 | Contact Author | By: Charles Fox, Independent Consultant
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Title: Stable O/W Nanoemulsions for Skin and Other Topics: Literature Findings
patentsx o/w nanoemulsionsx inhibiting melaninx pyrazolylpyrimidinex fluorescent pigment flakesx solubility of activesx and popping foam in aerosolsx among others.x
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Keywords: patents | o/w nanoemulsions | inhibiting melanin | pyrazolylpyrimidine | fluorescent pigment flakes | solubility of actives | and popping foam in aerosols | among others.

Abstract: This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development, including stable o/w nanoemulsions for skin, inhibiting melanin production with pyrazolylpyrimidine, fluorescent pigment flakes for color cosmetics, enhancing the solubility of actives, and popping foam in aerosols, among others.

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C Fox, Technically speaking—Stable o/w nanoemulsions for skin and other topics: Literature findings, Cosm & Toil 125(3) 30-38 (Mar 2010)

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This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development, including stable o/w nanoemulsions for skin, inhibiting melanin production with pyrazolylpyrimidine, fluorescent pigment flakes for color cosmetics, enhancing the solubility of actives, and popping foam in aerosols, among others.

Skin and Skin Care

Oxidative stress protection: L’Oréal has disclosed cosmetic compositions comprising a Gentianaceae plant extract and at least one superoxide dismutase (SOD) to protect the skin against the effects of oxidative stress from UV radiation, toxins or pollution.

Soothing ellagic acid: Beiersdorf AG has patented an ellagic acid-containing skin care preparation for soothing stressed and slightly damaged, irritated skin. Synthetic ellagic acid or ellagic acid extracted from plants such as raspberries, pomegranate, strawberries, blackberries and walnuts was used in aftershave preparations and diaper creams, which were prepared in combination with other actives. No examples were given.

Concealing skin irregularities: Shiseido Co., Ltd. has disclosed a cosmetic preparation for concealing skin irregularities. The preparation contained 0.5–3.0% hydrocarbon wax, comprising: a 20–95% wax moiety constituted of hydrocarbons having 28–42 carbon atoms, and a 5.0–80.0% wax moiety constituted of hydrocarbons having 43 or more carbon atoms; where the content of a moiety constituted of 27 or fewer carbon atoms is 15% or lower. The preparation also contained 0.1–5.0% fumed silica and 5.0–40.0% silicone elastomer powder.

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Footnotes

a Dehyquart L 80 (INCI: Dicocoylethyl Hydroxyethylmonium Methosulfate (and) Propylene Glycol) is a product of Cognis Care Chemicals, Monheim am Rhein, Germany.
b Nikkol TL 10 (INCI: PEG-20 Sorbitan Cocoate) is a product of Nikkol, Tokyo.
c Neosolue-MP (INCI: Methylpentanediol Dineopentanoate) is a product of Nippon Fine Chemical Co., Ltd., Tokyo.
d Genapol T250 (INCI: Ceteareth-25) is a product of Clariant, Muttenz, Switzerland.
e Aristoflex HMB (INCI: Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer) is a product of Clariant, Muttenz, Switzerland.
f Abil WE 09 (INCI: Polyglyceryl-4 Isostearate (and) Cetyl PEG/PPG-10/1 Dimethicone (and) Hexyl Laurate) is a product of Evonik Goldschmidt GmbH, Essen, Germany.
g Abil Wax 9801 (INCI: Cetyl Dimethicone) is a product of Evonik Goldschmidt GmbH, Essen, Germany.
h Abil Quat 3473 (INCI: Quaternium-80) is a product of Evonik Goldschmidt GmbH, Essen, Germany.
j Nikkol HCO 20 (INCI: Ethoxylated Hydrogenated Castor Oil) is a product of Nikkol.
k Emalex GWIS-120 (INCI: PEG-20 Glyceryl Isostearate) is a product of Nihon Emulsion Co., Ltd.

Formula 1. Skin protection composition1

SOD from wheat germ extract 0.002% w/w
Gentian root extract 0.050
Disodium EDTA 0.050
Tocopherol acetate 0.050
Ellagic acid 0.500
Glycolic acid 0.060
Butylene glycol 4.000
Emollients 2.000
Fatty alcohol 0.200
Fatty acids 2.250
Surfactants 0.300
Xanthan gum 0.250
Glycerin 5.000
Water (aqua) qs to 100.000

Formula 2. Cream for correcting skin irregularities3

Fischer-Tropsch wax 3.00% w/w
Methylpolysiloxane 5.00
Octyl methoxycinnamate 5.00
Isostearic acid 3.00
Silica dimethyl silylate (Aerosil R972, Evonik) 0.50
Dimethicone-vinyldimethicone crosspolymer 10.00
Dimethicone-vinyldimethicone-methicone crosspolymer 5.00
Polymethyl methacrylate 5.00
Zinc oxide 10.00
Decamethylcyclopentasiloxane qs to 100.00

Formula 3. Shampoo for blonde-colored hair5

Glycerin 12.00% w/w
Cetearyl alcohol 4.70
Cetrimonium chloride 3.80
bis-Diglyceryl polyacyladipate 2.00
Methylparaben 0.25
Propylparaben 0.10
Hydroxymethylcellulose 0.19
Cetearyl alcohol (and) behentrimonium chloride 0.20
Oryzanol  0.05
Citric acid qs
Sodium hydroxide qs
Fragrance (parfum) qs
Helianthus annus   0.01
Triticum vulgare  0.01
Mica (and) CI 77891 0.70
Mica (and) CI 77491 (and) alumina 0.25
Water (aqua) qs to 100.00

Formula 4. Hair styling emulsion6

Candelilla wax 2.00% w/w
Microcrystalline wax 12.00
Mineral oil 3.50
Hydrogenated polyisobutene 3.50
Pentaerythritol tetra-2-ethylhexanoate 3.00
Polyoxyethylene glyceryl isostearate 1.00
Glyceryl stearate 1.00
Behenyl alcohol 3.30
Stearyl alcohol 0.90
Tocopherol 0.50
Fragrance (parfum) 0.10
Propylene glycol 8.00
Sodium N-stearoyl-N-methyltaurine 1.20
Silica 2.50
Triethanolamine 4.00
Polyvinylpyrrolidone-vinyl acetate copolymer 1.80
Water (aqua) qs to 100.00

Formula 5. Hair dye7

Monoethanolamine 2.00% w/w
Polyoxyethylene oleocetyl alcohol 4.00
Polyoxyethylene lauryl alcohol 8.00
Polyoxyethylene decyl alcohol  6.00
Cetylstearyl alcohol 13.00
Lauric acid  5.00
Propylene glycol 8.00
Hexadimethrine chloride (Mexomere PO, Chimex) 1.00
Polyquaternium-6 (Merquat-100, Nalco) 2.00
Glycol distearate  4.00
Silica 2.00
4,5-Diamino-1-(2-hydroxyethyl)-H-pyrazole sulfate 2.00
2,4-Diaminophenoxyethanol dihydrochloride 0.64
3-Amino-2-methylamino-6-methoxypyridine dihydroxychloride 0.53
Ammonium hydroxide, 5% 11.00
Reducing agent qs
Antioxidant qs
Fragrance (parfum) qs
Sequestrant qs
Water (aqua) qs to 100.00

        

Formula 6. Antiperspirant9

Aluminum chlorohydrate 20.00% w/w
Mica (and) titanium dioxide 0.70
Fragrance (parfum) 1.00
Dimethicone 0.50
Cetearyl alcohol  2.50
Ceteareth-33  1.25
Water (aqua) qs to 100.00

Formula 7. Sprayable Antiperspirant/deodorant10

Cyclopentasiloxane (and) cyclohexasiloxane (Dow Corning 345 Fluid, Dow Corning)  16.70% w/w
Propylene glycol 9.10
PEG/PPG-18/18 dimethicone 1.40
Ethylhexylpalmitate 2.30
Aluminum chlorohydrate (Micro Dry, Reheis) 33.00
Cooling agent 0.50
Porous polyamide beads 0.50
Fragrance (parfum) 1.00
Water (aqua) qs to 100.00

Formula 8. Stabilized UVA sunscreen11

Polydimethylsiloxane 0.50% w/w
Preservative 1.00
Stearic acid 1.50
Glyceryl stearate-PEG stearate mixture 1.00
Complexing agent 0.10
C12-15 alkyl benzoate 20.00
4-tert-butyl-4’-methoxydibenzoylmethane 2.00
Glycerol 5.00
Xanthan gum 0.20
Monocetyl phosphate 1.00
Isohexadecane 1.00
Acrylic acid-stearyl methacrylate copolymer 0.20
Cetyl alcohol 0.50
Triethanolamine 0.65
Cetylstearyl glucoside (and) cetostearyl alcohol 2.00
Water (aqua) qs to 100.00

Formula 9. Allaying pollen allergies15

Lanolin alcohol 3.00% w/w
Microcrystalline wax 15.00
Microcrystalline wax (and) mineral oil 41.00
Mineral oil 38.75
Glycerin 1.00
Bisabolol 0.25
Panthenol 1.00
  100.00

Formula 10. Dry personal care composition16

Water (aqua) 23.40% w/w
Glycerin 2.90
Polyvinyl alcohol (Celvol 523, Celanese) 7.30
Ammonium laureth-3 sulfate 40.00
Ammonium lauryl sulfate 24.00
Cetyl alcohol 0.90
Cocamide MEA 1.50
  100.00

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