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Patent Picks—Dendrobium huoshanense, Novel Skin Surface Markers, Cyclodextrin Delivery and More in Skin
By: Rachel L. Grabenhofer
Posted: March 26, 2013
page 4 of 4
Cyclodextrin-based polymers for therapeutics delivery
US Patent 8404662
Publication date: March 26, 2013
Assignee: Cerulean Pharma Inc., Insert Therapeutics Inc. and Calando Pharmaceuticals Inc.
Disclosed in this patent are novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic. Furthermore, by selecting from a variety of linker groups and targeting ligands, the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein.
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