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Patents
New in Patents (page 15 of 20)
Apr 24, 2006 | 11:06 AM CDT
Technically Speaking
By: Charles Fox
From Assessing Hypopigmenting Agents to Translucent Cosmetic Solutions Ascorbic acid on collagen: Garcia-Mercier investigated the effect of a w/o emulsion containing ascorbic acid on collagen neosynthesis in human full thickness skin discs in culture.1 The response of human skin disks to agents having the ability to increase collagen synthesis was investigated. Seven experiments were performed, each using skin disks obtained from female patients. L-ascorbic acid in the culture medium was incubated with skin for 72 hours. Collagen synthesis was evaluated by measuring 3H-proline incorporation into dermis proteins. Expected effects were found and results were shown to be reproducible. Two cosmetic formulations – a clear solution and a w/o emulsion containing L-ascorbic acid – were then tested by topical application on the human skin disks and incubated for 72 hours.
Apr 12, 2006 | 07:47 AM CDT
Technically Speaking
By: Charles Fox
From Investigating Aging to Acrylic Polymers in Sunscreens Sauermann et al. have investigated age-related changes of human skin with histometric measurements by confocal laser scanning microscopy in vivo.1 The confocal laser scanning microscope allows skin to be studied in real-time with a resolution of 0.5 mm horizontal and 1.3 m vertical in vivo. In this study, the authors present the results of a comparison between the skin of an older and a younger group of volunteers by in vivo histometric measurements. To investigate changes caused by age, 13 young (18-25years) and 13 older (>65years) volunteers were examined.
Feb 07, 2006 | 10:57 AM CST
Foamix Awarded American, Australian Patents for Delivery Technology
Foamix Ltd. announced it has received two separate patents for its delivery system/carrier technology.
Dec 23, 2005 | 06:02 PM CST
Sunscreen Efficacy Validation and Other Topics
By: Charles Fox, Independent Consultant
Care pH on epidermal permeability: Hachem et al. have studied the effect of pH on epidermal permeability and skin barrier homeostasis.
Dec 23, 2005 | 05:43 PM CST
Topical Vitamins and Other Topics
By: Charles Fox, Independent Consultant
Care Sunless tanning with dihydroxyacetone: Nguyen et al. have studied the factors influencing sunless tanning with dihydroxyacetone. Sunless tanning preparations have been used for more than 50 years and are still very popular because they provide temporary pigmentation resembling an ultraviolet-induced tan. The pigment is the product of reactions between dihy-droxy-acetone (DHA) and amino acids in the stratum corneum.
Dec 23, 2005 | 05:27 PM CST
A Novel Whitening Agent and Other Topics
By: Charles Fox, Independent Consultant
Care Frequency of fragrance allergy: Buckley et al. investigated the frequency of fragrance allergy in patch-tested patients. The most likely age of sensitization to fragrance chemicals is unknown. These investigators patch tested 23,846 patients over a 14-year period. They report that 8.4% of the females and 6.4% of the males tested were allergic to fragrance materials. The frequency of fragrance allergy was low in the first two decades of life. It gradually increased in females after the age of 20 years and peaked in the 60-year range at 14.45 of those tested. The authors conclude that the findings support the hypothesis that allergy to fragrance results from a combination of repeated environmental exposure and age-related susceptibility factors.
Dec 23, 2005 | 05:14 PM CST
A Foaming Cleanser and Other Topics
By: Charles Fox, Independent Consultant
Care Isoflavonoids in skin care: Beiersdorf discloses the use of isoflavonoids to fight skin aging and acne. The invention concerns cosmetic and dermatological preparations that contain isoflavonoids and cyclodextrins. Cyclodextrins are added in order to increase the solubility of the isoflavonoids in the preparations that are applied against skin aging and acne. An example is shown in Formula 1.
Dec 23, 2005 | 04:40 PM CST
Emulsions Including Cross-Linked Oil Drops and Other Topics
By: Charles Fox, Independent Consultant
Trommer et al have published on the effects of hyaluronan (sodium hyaluronate) and its fragments on lipid models exposed to UV irradiation.
Dec 23, 2005 | 04:26 PM CST
Epidermal Permeability Barrier and Other Topics
By: Charles Fox
A historical review on the epidermal permeability barrier: Elias has published a historical review on the epidermal permeability barrier dating from the early days at Harvard to newly emerging concepts. This is a must-read article if you are the least bit interested in skin physiology. I will attempt to cover the highlights here. Elias begins with the statement, “Perhaps no tissue is so physically maligned by processing for light/electron microscopy as is the stratum corneum (SC). To further complicate matters, no tissue of such critical importance for survival has been so intellectually maligned as well.” He then traces the work of now famous investigators including Kligman, Blank and Scheuplein.
Dec 23, 2005 | 04:20 PM CST
Focus on Technology Transfer—Creativity
By: Larry Plonsker, Chemical Network Associates
We have described technology transfer as the bridge between invention and innovation. Innovation is the process of taking ideas, inventions or concepts to a successful commercial conclusion. The importance of innovation in the U.S. economy was the subject of a recent Thomas Friedman article in the New York Times.1 In Bangalore, India, Friedman asked a Ph.D. economist from a U.S. university how she felt about the outsourcing of U.S. jobs to India. She replied with a story about a man in America who lost his job this way but made a good business of selling T-shirts that complained about losing a job to India, and not getting anything but “this [lousy] T-shirt.” Her comment was “only in America would someone figure out how to profit from his own unemployment.”