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Patent Picks—Skin Imaging, Carnitine Creatine for Skin, Sclareol for Antiaging and More

By: Rachel Grabenhofer
Posted: July 28, 2010

page 2 of 7

The composition is reportedly useful in preventing, ameliorating or treating: acne, oily skin, oily hair, oily scalp, skin blemishes, breakouts and improves skin texture. According to the patent, the composition may be applied to the skin one or more times per day to maintain a desirable aesthetic appearance to the skin or maintain skin’s appearance as being substantially free of cellulite. Typically, beneficial results are observed following daily application of the topical composition for a period of one week.

In another aspect of the invention, a hydrogel patch is used to incorporate the carnitine creatinate, which is admixed with a hydrogel base. The patch can be affixed to an area of the skin where an individual aims to reduce the appearance of fat; for example, the inner thigh. The patch is applied for four or more hours per day for one or two days, after which the patch is removed. A second patch is then affixed, and the process is repeated over an extended period of time—from four up to 12 weeks.

Topical Solution Containing a Chromane or Chromene Derivative
US Patent 7763647
Publication Date: July 27, 2010
Assignee: Laboratories Expanscience (Courbevoie, France)

This invention relates to compositions intended for external topical use comprising a solution containing a chromane or chromene derivative, preferably a flavonoid, dissolved in a suitable solvent. The invention also relates to a method for preparing such compositions and the use of said compositions as sun protection agents for the skin with benefits including anti-erythemal, antioxidant, anti-radical, anti-inflammatory or vasculotropic activities.

According to the patent, natural or synthetic compounds of the flavonoid type, such as flavones, flavanones, flavonols, aurones and chalcones, are potent antioxidants and often exhibit high inhibitory activities for enzymes in general. In particular, genistein is known as a preventive agent against skin problems including cancers induced by UV radiation (WO 97/46208). Genistein may thus be administered by the topical route in order to prevent and treat skin inflammations and irritations such as erythemas.