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From Caper to Prickly Pear for Dermatitis to Dual Phase Mouthwash: Literature Review

Formulas

  • Formula 1. Moisturizing night cream1

    Formula 1. Moisturizing night cream1

    Carbamate-containing polysiloxane (preparation given) 2.00% w/w
    Mineral oil 17.00
    Hydrogenated castor oil 0.40
    Microcrystalline wax 0.60
    Sodium chloride 0.50
    Urea 10.00
    Phenoxyethanol (and) methylparaben (and) piroctone olamine (Nipaguard POM, Clariant) 0.80
    Fragrance (parfum) qs
    Water (aqua) qs to 100.00
  • Formula 2. Hair softener7

    Formula 2. Hair softener7

    Cetostearyl alcohol 9.00% w/w
    Octyldodecanol 3.00
    Cetyltrimethylammonium chloride 3.00
    Polyoxyethylene sorbitol tetraoleate (Nikkol GO-4V, Nikko) 2.00
    Polyoxyethylene stearyl ether (Nikkol BS-2, Nikko) 4.00
    Water (aqua) qs to 100.00
  • Formula 3. Shampoo8

    Formula 3. Shampoo8

    Sodium laureth sulfate 11.20% w/w
    Cocamidopropyl betaine 1.80
    Oxidized hydroxyethyl cellulose 0.40
    Citric acid qs to pH 5.6
    Water (aqua) qs to 100.00
  • Formula 4. Hair dye9

    Formula 4. Hair dye9

    Amine compatible silicone adhesive (Bio PSA 7-4405, Dow Corning) 20.00% w/w
    Cyclopentasiloxane (and) dimethiconol (DC 1501 Fluid, Dow Corning) 10.00
    Polymethylsilsesquioxane (Wacker Belsil PMS MK Powder, Wacker-Chemie) 3.00
    Colored earth 8.00
    Isododecane qs to 100.00
  • Formula 5. Lip gloss11

    Formula 5. Lip gloss11

    Dimethyl silylate 2.00% w/w
    CI 77491 (and) CI 77492 0.26
    CI 77499 0.04
    CI 15850 0.23
    CI 77891 0.15
    Prunus dulcis 24.00
    Pentaerythritol tetraisostearate 10.00
    Helianthus annuus seed wax 5.00
    Dimer dilinoleyl dimer dilinoleate 35.00
    Dilinoleic acid/butanediol copolymer 10.00
    Octyldodecanol qs to 100.00
  • Formula 6. Film-forming lip preparation12

    Formula 6. Film-forming lip preparation12

    Polyethylene glycol 1.00% w/w
    Methylparaben 0.20
    Polyvinyl alcohol 9.50
    Glycerin 5.00
    Xanthane polysaccharides 1.00
    Dimethyl isosorbide 1.50
    Ethoxylated polydimethylsiloxane 2.00
    Hydrogenated isoparaffin 1.00
    Ethanol 8.00
    Trisodium citrate dihydrate 0.02
    Vinyl acetate-vinylpyrrolidone copolymer 2.67
    Water (aqua) qs to 100.00
  • Formula 7. O/W sunscreen emulsion13

    Formula 7. O/W sunscreen emulsion13

    Glyceryl stearate citrate 2.00% w/w
    Stearyl alcohol 0.50
    Myristyl myristate 1.00
    Acrylate/C10-30 alkyl acrylate crosspolymer 0.10
    Xanthan gum 0.40
    Butylene glycol dicaprylate/dicaprate 5.00
    Dicaprylcaprate 2.00
    1,2-Hexanediol 0.20
    Glycerin 7.50
    Trisodium citrate dihydrate 0.02
    Ethyl alcohol 2.00
    Titanium dioxide (and) aluminum hydroxide (and) dimethicone/methicone copolymer (particle size 15 nm) 3.00
    Titanium dioxide (and) dimethicone/methicone copolymer (particle size 80 nm) 2.00
    Ethylhexyltriazine 2.50
    2-(4’-Diethylamino-2’-hydroxybenzoyl) benzoic acid hexyl ester 2.00
    Ethylhexylsalicylate 2.00
    Vitamin E acetate 0.20
    Disodium EDTA 0.10
    Fragrance (parfum) qs
    Preservative qs
    NaOH qs
    Water (aqua) qs to 100.00
  • Formula 10. W/O Foundation18

    Formula 10. W/O Foundation18

    Silicone dendrimer acrylic copolymer 5.00% w/w
    Dimethylpolysiloxane polyoxyethylene copolymer 0.50
    Decamethylcyclopentasiloxane 10.00
    Dimethylpolysiloxanes 16.00
    2-Ethylhexyl p-methoxycinnamate 3.00
    Glycerin 2.00
    Ethanol 7.00
    Magnesium sulfate 0.50
    Silicone-treated zinc oxide (and) titanium oxide (and) iron oxide (and) mica 12.80
    Silsesquioxane 2.50
    Water (aqua) qs to 100.00
  • Formula 9. Pressurized composition17

    Formula 9. Pressurized composition17

    Water (aqua) 96.30% w/w
    Potassium phosphate, 50% 1.00
    Ethoxylated (60) hydrogenated castor oil, 50% 0.50
    C6-17 secondary alcohol 0.30
    3-6 mol Ethoxylate didecyldimethyl ammonium chloride, 50% 0.10
    Permethrin 0.50
    Propylene glycol 0.40
    Polyhexamethylene biguanide 0.20
    Nitrogen 0.70
      100.00
  • Formula 8. Dual-phase mouthwash14

    Formula 8. Dual-phase mouthwash14

    Mineral oil 13.00% w/w
    Water (aqua) 60.00
    Glycerin 9.00
    Propylene glycol 9.00
    Sorbitol 5.00
    Sodium pyrophosphate 0.50
    Potassium pyrophosphate 1.40
    Maleic anhydride vinyl methyl ether copolymer 0.30
    Sodium fluoride 0.05
    Flavor and colors 1.745
    Nonionic surfactant 0.005
      100.00
By: Charles Fox (See In Memory Sidebar)
Posted: June 29, 2010, from the July 2010 issue of Cosmetics & Toiletries.

This month’s survey of recent patent and research literature describes money-making ideas for personal care product development, including indirect antioxidants for skin protection, caper and prickly pear extracts to address skin conditions, granulated shampoo and a dual phase mouthwash, among others.

Skin and Skin Care
Polysiloxane emulsifiers: Clariant International Ltd. discloses cosmetic or pharmaceutical compositions, preferably emulsions, utilizing one or more modified polysiloxanes with at least one carbamate group as the emulsifiers.1 An example of an extra moisture night cream is shown in Formula 1.

Vernonia to improve skin: Bayer Consumer Care describes the use of Vernonia extract to improve skin.2 The described invention incorporates a Vernonia plant extract from Madagascar into cosmetics, pharmaceuticals and food supplements to improve the skin by strengthening the dermal-epidermal junction and/or activating fibroblast synthesis and extracellular matrix compounds.

Thus, dried leaves of Vernonia appendiculata were extracted using heptane and percolated with ethanol. The fats were then removed by liquid-liquid extraction, also using heptane. After concentration into the aqueous phase, glycerin was added to adjust the solution to 10% extract in a water-glycerin blend. The final product resulted in a liquid containing > 5% of chlorogenic and isochlorogenic acids. The end Vernonia extract obtained was formulated at 1% into an antiaging cream.

Topical, injectable hyaluronan and heparin: Innoderm has patented topical and injectable cosmetic or pharmaceutical compositions containing a combination of cross-linked or non-cross-linked hyaluronan and heparin and/or one or more heparinoid derivatives.3 These compositions were employed to prolong the lifespan of the hyaluronan present in the skin, which is either endogenous or exogenous, cross-linked or non-cross-linked, in order to improve its antiaging and moisturizing actions and to fill in wrinkles.