Stable O/W Nanoemulsions for Skin and Other Topics: Literature Findings
Formulas
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Formula 1. Skin protection composition1
Formula 1. Skin protection composition1
SOD from wheat germ extract 0.002% w/w Gentian root extract 0.050 Disodium EDTA 0.050 Tocopherol acetate 0.050 Ellagic acid 0.500 Glycolic acid 0.060 Butylene glycol 4.000 Emollients 2.000 Fatty alcohol 0.200 Fatty acids 2.250 Surfactants 0.300 Xanthan gum 0.250 Glycerin 5.000 Water (aqua) qs to 100.000 - Formula 2. Cream for correcting skin irregularities3
Formula 2. Cream for correcting skin irregularities3
Fischer-Tropsch wax 3.00% w/w Methylpolysiloxane 5.00 Octyl methoxycinnamate 5.00 Isostearic acid 3.00 Silica dimethyl silylate (Aerosil R972, Evonik) 0.50 Dimethicone-vinyldimethicone crosspolymer 10.00 Dimethicone-vinyldimethicone-methicone crosspolymer 5.00 Polymethyl methacrylate 5.00 Zinc oxide 10.00 Decamethylcyclopentasiloxane qs to 100.00 - Formula 3. Shampoo for blonde-colored hair5
Formula 3. Shampoo for blonde-colored hair5
Glycerin 12.00% w/w Cetearyl alcohol 4.70 Cetrimonium chloride 3.80 bis-Diglyceryl polyacyladipate 2.00 Methylparaben 0.25 Propylparaben 0.10 Hydroxymethylcellulose 0.19 Cetearyl alcohol (and) behentrimonium chloride 0.20 Oryzanol 0.05 Citric acid qs Sodium hydroxide qs Fragrance (parfum) qs Helianthus annus 0.01 Triticum vulgare 0.01 Mica (and) CI 77891 0.70 Mica (and) CI 77491 (and) alumina 0.25 Water (aqua) qs to 100.00 - Formula 4. Hair styling emulsion6
Formula 4. Hair styling emulsion6
Candelilla wax 2.00% w/w Microcrystalline wax 12.00 Mineral oil 3.50 Hydrogenated polyisobutene 3.50 Pentaerythritol tetra-2-ethylhexanoate 3.00 Polyoxyethylene glyceryl isostearate 1.00 Glyceryl stearate 1.00 Behenyl alcohol 3.30 Stearyl alcohol 0.90 Tocopherol 0.50 Fragrance (parfum) 0.10 Propylene glycol 8.00 Sodium N-stearoyl-N-methyltaurine 1.20 Silica 2.50 Triethanolamine 4.00 Polyvinylpyrrolidone-vinyl acetate copolymer 1.80 Water (aqua) qs to 100.00 - Formula 5. Hair dye7
Formula 5. Hair dye7
Monoethanolamine 2.00% w/w Polyoxyethylene oleocetyl alcohol 4.00 Polyoxyethylene lauryl alcohol 8.00 Polyoxyethylene decyl alcohol 6.00 Cetylstearyl alcohol 13.00 Lauric acid 5.00 Propylene glycol 8.00 Hexadimethrine chloride (Mexomere PO, Chimex) 1.00 Polyquaternium-6 (Merquat-100, Nalco) 2.00 Glycol distearate 4.00 Silica 2.00 4,5-Diamino-1-(2-hydroxyethyl)-H-pyrazole sulfate 2.00 2,4-Diaminophenoxyethanol dihydrochloride 0.64 3-Amino-2-methylamino-6-methoxypyridine dihydroxychloride 0.53 Ammonium hydroxide, 5% 11.00 Reducing agent qs Antioxidant qs Fragrance (parfum) qs Sequestrant qs Water (aqua) qs to 100.00 - Formula 6. Antiperspirant9
Formula 6. Antiperspirant9
Aluminum chlorohydrate 20.00% w/w Mica (and) titanium dioxide 0.70 Fragrance (parfum) 1.00 Dimethicone 0.50 Cetearyl alcohol 2.50 Ceteareth-33 1.25 Water (aqua) qs to 100.00 - Formula 7. Sprayable Antiperspirant/deodorant10
Formula 7. Sprayable Antiperspirant/deodorant10
Cyclopentasiloxane (and) cyclohexasiloxane (Dow Corning 345 Fluid, Dow Corning) 16.70% w/w Propylene glycol 9.10 PEG/PPG-18/18 dimethicone 1.40 Ethylhexylpalmitate 2.30 Aluminum chlorohydrate (Micro Dry, Reheis) 33.00 Cooling agent 0.50 Porous polyamide beads 0.50 Fragrance (parfum) 1.00 Water (aqua) qs to 100.00 - Formula 8. Stabilized UVA sunscreen11
Formula 8. Stabilized UVA sunscreen11
Polydimethylsiloxane 0.50% w/w Preservative 1.00 Stearic acid 1.50 Glyceryl stearate-PEG stearate mixture 1.00 Complexing agent 0.10 C12-15 alkyl benzoate 20.00 4-tert-butyl-4’-methoxydibenzoylmethane 2.00 Glycerol 5.00 Xanthan gum 0.20 Monocetyl phosphate 1.00 Isohexadecane 1.00 Acrylic acid-stearyl methacrylate copolymer 0.20 Cetyl alcohol 0.50 Triethanolamine 0.65 Cetylstearyl glucoside (and) cetostearyl alcohol 2.00 Water (aqua) qs to 100.00 - Formula 9. Allaying pollen allergies15
Formula 9. Allaying pollen allergies15
Lanolin alcohol 3.00% w/w Microcrystalline wax 15.00 Microcrystalline wax (and) mineral oil 41.00 Mineral oil 38.75 Glycerin 1.00 Bisabolol 0.25 Panthenol 1.00 100.00 - Formula 10. Dry personal care composition16
Formula 10. Dry personal care composition16
Water (aqua) 23.40% w/w Glycerin 2.90 Polyvinyl alcohol (Celvol 523, Celanese) 7.30 Ammonium laureth-3 sulfate 40.00 Ammonium lauryl sulfate 24.00 Cetyl alcohol 0.90 Cocamide MEA 1.50 100.00 By: Charles Fox, Independent Consultant
Posted: February 26, 2010, from the March 2010 issue of Cosmetics & Toiletries.
This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development, including stable o/w nanoemulsions for skin, inhibiting melanin production with pyrazolylpyrimidine, fluorescent pigment flakes for color cosmetics, enhancing the solubility of actives, and popping foam in aerosols, among others.
Skin and Skin Care
Oxidative stress protection: L’Oréal has disclosed cosmetic compositions comprising a Gentianaceae plant extract and at least one superoxide dismutase (SOD) to protect the skin against the effects of oxidative stress from UV radiation, toxins or pollution.1 An example is shown in Formula 1.Soothing ellagic acid: Beiersdorf AG has patented an ellagic acid-containing skin care preparation for soothing stressed and slightly damaged, irritated skin.2 Synthetic ellagic acid or ellagic acid extracted from plants such as raspberries, pomegranate, strawberries, blackberries and walnuts was used in aftershave preparations and diaper creams, which were prepared in combination with other actives. No examples were given.
Concealing skin irregularities: Shiseido Co., Ltd. has disclosed a cosmetic preparation for concealing skin irregularities. The preparation contained 0.5–3.0% hydrocarbon wax, comprising: a 20–95% wax moiety constituted of hydrocarbons having 28–42 carbon atoms, and a 5.0–80.0% wax moiety constituted of hydrocarbons having 43 or more carbon atoms; where the content of a moiety constituted of 27 or fewer carbon atoms is 15% or lower. The preparation also contained 0.1–5.0% fumed silica and 5.0–40.0% silicone elastomer powder.3 An example is shown in Formula 2.
Pyrazolylpyrimidine to inhibit melanin: Shiseido Company Ltd. also has disclosed skin whitening agents comprising pyrazolylpyrimidine derivatives with excellent melanin production-inhibiting activity.4 An external preparation for the skin containing the compound also is disclosed. For example, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-4,6-dimethylpyrimidine was prepared and tested in vitro for melanin production-inhibiting activities.
Hair and Hair Care
- Formula 2. Cream for correcting skin irregularities3