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Delivery with Chitosan-coated Liposomes and Other Topics: Literature Findings
By: Charles Fox, Independent Consultant
Posted: February 26, 2009, from the March 2009 issue of Cosmetics & Toiletries.
- Formula 1. W/O moisturizing day cream2
- Formula 2. Antiaging cosmetic3
- Formula 3. Self-adhesive gel skin mask4
- Formula 4. Hair styling gel5
- Formula 5. Oily nonsticky lipstick6
- Formula 6. Nail growth treatment8
- Formula 7. O/W sunscreen lotion12
- Formula 8. Lipid microemulsion14
- Formula 9. Transparent lipstick18
- Formula 10. Hair styling treatment18
This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development including the chitosan-coated liposome delivery of tamarind, luminescent pigments, microemulsions and laudanosine for antiaging, among others.
Skin and Skin Care
Skin moisturization: Tomaru has published a review on moisturizing products for the skin.1 Moisturization is an important claim for skin care products. The stratum corneum (SC) has its own water-holding mechanisms but they are not always enough. Successful ways to moisturize skin include humectants and emollients that are adapted to the skin’s condition and the natural water-holding mechanisms.
Formulators can improve upon the water-holding ability of humectants by adjusting the microstructure of the ingredients; for example, with liposomes and other lamellar structures. Furthermore, improvement of total skin condition can be achieved by applying ingredients that promote the production of a moisturizing factor. An example of such an ingredient is an extract of rice in combination with water,a which has been shown to increase the amount of ceramides, the main components of intercellular lipids.
W/O emulsion to prevent TEWL: L’Oréal discloses a skin care w/o emulsion for topical application comprising at least one emulsifying silicone elastomer and at least one semi-crystalline polymer.2 The invention relates to the use of the composition or skin care, in particular for nourishing the skin, preventing transepidermal water loss and protecting the skin. The disclosed composition for a w/o moisturizing day cream is shown in Formula 1.
Liquid crystal composition: Bioentech Co., Ltd., discloses a liquid crystal composition, its manufacturing method and the cosmetic composition containing it.13 The liquid crystal composition contains saturated lecithin, cetyl alcohol, stearyl alcohol and glyceryl stearate. According to the inventors, based on the lamella-forming capability of lecithin, other components and an additional coating process are not necessary. The liquid crystal composition exhibits improved stability and moisturizing effects and reportedly bears a likeness to skin. The composition is capable of reducing water loss and can be widely used in cleansers. The invention also relates to a method for manufacturing the liquid crystal composition.