Sauermann et al. have investigated age-related changes of human skin with histometric measurements by confocal laser scanning microscopy in vivo.1 The confocal laser scanning microscope allows skin to be studied in real-time with a resolution of 0.5 mm horizontal and 1.3 m vertical in vivo. In this study, the authors present the results of a comparison between the skin of an older and a younger group of volunteers by in vivo histometric measurements. To investigate changes caused by age, 13 young (18-25years) and 13 older (>65years) volunteers were examined.
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