Evaluating Outside-in Skin Transparency and Other Literature Findings

Sep 1, 2009 | Contact Author | By: Charles Fox, Independent Consultant
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Title: Evaluating Outside-in Skin Transparency and Other Literature Findings
patentsx
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Keywords: patents

Abstract: This month’s survey of recent patent and research literature describes moneymaking ideas for personal care product development including curcumin for antiaging, a two-bead plurality skin cleanser, a storage-stable hair color kit, and the evaluation of outside-in skin transparency, among others.

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Skin and Skin Care 
Dermcidin: Readers interested in keeping up with skin physiology should read the study by Niyonsaba et al. on the human antimicrobial peptide dermicidin and its behavior in activating normal human keratinocytes.1 To protect against invading microbial pathogens, the skin has evolved various mechanisms including epithelial defenses, which mainly consist of antimicrobial proteins and peptides.

In the skin, both resident and infiltrating cells synthesize and secrete small peptides that exhibit broad-spectrum antimicrobial activity against bacteria, fungi and viruses. However, it is increasingly evident that these peptides act not only as endogenous antibiotics, but also are involved in immune and/or inflammatory responses.

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Footnotes

aRoxisomes (INCI: Arabidopsis Thaliana Extract (and) Lecithin (and) Water (aqua)) is a product of Barnet Products Corp., Englewood Cliffs, N.J., USA.
bUltrasomes V (INCI: Micrococcus Lysate) is a product of Barnet Products Corp., Englewood Cliffs, N.J., USA.
cSFE 839 (INCI: Cyclopentasiloxane (and) Dimethicone/Vinyl Dimethicone Crosspolymer) is a product of Momentive Performance Materials, Albany, N.Y., USA.
dSF-1202 (INCI: Cyclopentasiloxane) is a product of Momentive Performance Materials, Albany, N.Y., USA.
eCC-2509 Normal Human Dermal Fibroblasts, Neonatal, cryopreserved is a product of Lonza, Basel, Switzerland.
fFomblin HP/P2-1000 (INCI: Polyperfluoro-ethoxymethoxy Difluoroethyl PEG Phosphate) is a product of Solvay Solexis S.p.A., Milan, Italy.
gPemulen TR-1 (INCI: Acrylates/C10-30 Alkyl Acrylate Crosspolymer) is a product of The Lubrizol Corp., Wickliffe, Ohio, USA.
hTrefil E 506 (INCI: Crosslinked Methyl-polysiloxane Powder) is a product of Dow Corning, Midland, Mich., USA.
jKF-96L-5CS (Dimethicone) is a product of Shin Etsu Chemicals Co., Ltd., Tokyo.
kKF-96L-10CS (INCI: Dimethicone) is a product of Shin Etsu Chemicals Co., Ltd., Tokyo.
mCarbopol ETD 2020 (INCI: Acrylates/C10-30 Alkyl Acrylate Crosspolymer) is a product of The Lubrizol Corp., Wickliffe, Ohio, USA.

Formula 1. Hand and body cleanser with color-forming beads4

Sodium laureth sulfate (Texapon N-70, Cognis) 12.00% w/w
Cocamidopropyl betaine (Dehyton PK 45, Cognis) 9.00
Coco-glucoside (Plantacare 818, Cognis) 2.00
Polyquaternium-7 (Conditioner P7, 3V Group) 1.00
Panthenol 0.20
Glycol distearate (and) sodium laureth sulfate (and) cocamide MEA (and) laureth-10 (Euperlan PK810, Cognis) 0.50
Styrene/acrylates copolymer (Acusol OP-301, Rohm and Haas) 2.00
Beads A1 premix (see below) 3.00
Beads B1 premix (see below) 1.00
Ethylhexylglycerin (Sensiva SC 50, Schülke) 1.00
Water (aqua) qs to 100.00
   
Beads A1  
Mannitol 25.00–50.00
Cellulose 25.00–50.00
Hydroxypropyl methylcellulose < 1.00
Ultramarines  25.00–50.00
Magnesium stearate 5.00–10.00
   
Beads B1  
Cellulose 15.00–20.00
Hydroxypropyl methylcellulose 4.00–9.00
Lactose 25.00–32.00
Ultramarines 45.00–55.00
PVA 0.10–2.00

Formula 2. Water-based mascara12

Beeswax 10.00% w/w
Candelilla wax 10.00
Hydrogenated olive oil stearyl esters (Phytowax Olive 18L57, Sophim) 10.00
Potassium soyate 2.50
Potassium cocoate 0.25
Glycerol 0.29
Hydroxyethylcellulose 0.90
Iron oxide 7.00
Simethicone 0.20
Preservative qs
Water (aqua) qs to 100.00

Formula 3. Long-wear lip gloss13

Phenyl trimethicone 12.00% w/w
Isododecane 9.00
Polyglyceryl-4 isostearate (and) cetyl PEG/PPG-10/1 dimethicone (and) hexyl laurate 29.58
Silica silylate 3.50
Styrene/acrylates copolymer 15.00
PPG-51/SMDI copolymer 8.00
Trimethylsiloxyphenyl dimethicone 10.00
Cera microcristallina 2.50
1,2 Hexanediol (and) caprylyl glycol 2.00
Organic or inorganic dry color pigments 2.75
Mica (and) titanium dioxide 4.75
Mica 0.52
Fragrance (parfum) 0.40

    

Formula 4. Transparent silicone-in-water emulsion16

Bis-PEG/PPG-16/16 PEG/PPG16/16 dimethicone 1.00% w/w
Caprylic/capric triglyceride 1.00
Hydrogenated polyisobutene 0.50
Octyldodecanol 0.50
Glycerin 5.00
Panthenol 0.50
Fragrance (parfum) qs
Methylparaben 0.40
Propylparaben 0.30
Water (aqua) qs to 100.00

 

Formula 5. Pre-shave preparation18

Polyfluoroalkyl dimethicone polymer 2.00% w/w
Water (aqua) 16.40
Acrylate/C10-30 alkyl acrylate crosspolymer 0.60
Isodecyl myristate 2.00
Trimethylpropane triethylhexanoate 1.00
Alcohol 78.00

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