Patent Picks—Multipurpose Polymers, Improving Foam, Surfactant-containing Films and More

By: Rachel Grabenhofer

Posted: June 14, 2011

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Disclosed in this patent is an oral care composition and method in which the composition includes a film or a plurality of film fragments containing a high concentration of nonionic surfactants and entrained in a carrier. Both the composition and method provide benefits including higher active material loading in the film formula for improved efficacy and a reduced amount of film needed in a product, while at the same time delivering comparable or improved efficacy with lower loading of the film in the composition. This application specifically relates to such oral care compositions as dentifrices as their aesthetic appeal is important and can have significant effects on consumer acceptance and use.

Linear and cyclic siloxanes and cosmetic compositions made thereof
WIPO Patent Application WO/2011/068250
Publication date: June 9, 2011
Assignee: Dow Corning Toray Co., Ltd.; A Hayashi; T Iimura; H Furukawa; and H Kondo

The present invention describes a novel organopolysiloxane having a specified structure and a cosmetic containing it. The organopolysiloxane is volatile, possesses stability at low temperatures, provides superior glossiness and has a superior property with respect to miscibility with UV absorbers. In addition, it is useful as a replacement for octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, or methyltrimethicone. The cosmetic incorporating the organopolysiloxane can reportedly provide superior feeling to the touch during use and a superior outer appearance. It also provides an increased degree of freedom in blending various components such as UV absorbers into the cosmetic. Further, cosmetics of the present invention can incorporate combinations of dispersants, emulsifiers, cleansers, surface-treatment agents of other components, and one or more surfactants selected from anionic surfactants, cationic surfactants, nonionic surfactants, amphoteric surfactants and semi-polar surfactants.

In vitro method for testing toxicity and efficacy of a test material to an ocular surface
WIPO Patent Application WO/2011/067384
Publication date: June 9, 2011
Assignee: Novagali Pharma S.A.; J-S Garrigue; P Daull; C Baudouin; F Brignole-Baudouin; and H Liang

This patent describes an in vitro method and kit for testing toxicity through the characterization of the healing efficacy of a test material. The test method includes: a) performing a monolayered or multilayered culture of epithelial corneal or conjunctival cells including quiescent and dividing cells, with said culture being obtained by cultivating cells to confluence followed by the scraping of the cell layer(s) resulting into a cleft; b) applying the test material onto said culture; and c) measuring cell viability and closure of the cleft with the same culture treated with a reference solution, such as a saline solution.