Patent Picks—Cassia Deposition, Warming Substrates, Sol-gel Particles and More

By: Rachel L. Grabenhofer, Cosmetics & Toiletries magazine

Posted: April 20, 2011

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Use of siRNA targeting Sipa1l1 for the reduction of adipogenesis
European Patent Application EP2308892
Publication date: April 13, 2011
Assignee: Sanofi-aventis

The present invention concerns Sipa1I1, a new target involved in adipogenesis modulation. Using a siRNA approach, the inventors demonstrated that decrease in Sipa1I1 activity in preadipocytes and adipose tissue induces a decrease in adipogenesis. Thus, the present invention relates to modulators of Sipa1I1 activity as well as screening test for identification of modulators of the activity of this target, and their use, especially in pharmaceutical compositions, to modulate adipogenesis and thus treat obesity and related disorders.

Agent-encapsulating micro- and nanoparticles, methods for preparation of same and products containing same
US Patent 7923030
Publication date: April 12, 2011
Assignee: Sol-Gel Technologies Inc.

This patent relates to substantially non-leachable sol-gel particles and, more particularly, to sol-gel micro- and nanoparticles encapsulating one or more agents (e.g., colorants), characterized by unprecedented stability to leaching or migration of the agents from therein. The invention further relates to a method of producing the particles of the invention and to products containing them, such as, for example, cosmetic and oral care colored products.

Compositions including vitamin-based surfactants and methods for using same
US Patent 7923469
Publication date: April 12, 2011
Assignee: Allergen Inc.