Patent Picks—New Rodlike C.I. Pigment, Broad-spectrum Preservative; Sensory Activators and More

By: Rachel L. Grabenhofer

Posted: January 26, 2011

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The present invention describes a formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive that is also encapsulated within the exine shell. It is known from previous work that exine coatings of naturally derived, typically plant spores can be used as delivery vehicles for pharmaceuticals and dietetic substances. These coatings can be isolated from spores by successive treatments with organic solvents, alkali and acid so as to remove the lipid, carbohydrate, protein and nucleic acid components that may be attached to or contained within the exine shell. Enzymatic methods have also been used to isolate the exine coating from other components of a spore.

The invention thus proposes that a protective additive be co-encapsulated with the active substance, both within the exine shell, rather than applied as a coating around the external surface of the shell. This approach reportedly has been found to provide an effective degree of protection for the encapsulated active substance.

Antimicrobial

Topical antimicrobial compositions and uses thereof
US Patent Application 20100331276
Publication date: Dec. 30, 2010
Assignee: VirBac SA

This invention relates to a composition for topical application that comprises at least one first and one second mono- or oligosaccharide, each of said first and second mono- or oligosaccharides being capable of limiting the adhesion of microorganisms to the skin. According to the patent, the presence of a single mono- or oligosaccharide capable of limiting the adhesion of a limited number of families of specific pathogenic microorganisms. However, when a composition includes at least two mono- or oligosaccharides, the inhibition of the microorganisms affects a much larger number of families and an effective inhibition of the microorganisms is observed, thus the adherence of the pathogenic microorganisms on the skin is considerably reduced. The addition of a third mono- or oligosaccharide is also highly advantageous. Nevertheless, the addition of numerous other mono- or oligosaccharides reportedly appears to be of only minor benefit.