Patent Picks—Imaging Skin, Simulating Eyelashes, Assaying Immune Response and More

By: Rachel Grabenhofer

Posted: August 11, 2010

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Assay for inhibitors of protein kinase C-related kinases
US Patent 7767411
Publication Date: Aug. 3, 2010
Assignee: Universitaetsklinikum Freiburg (Freiburg, DE)

The present invention relates to an assay for specific inhibitors of protein kinase C-related kinases (PRKs) relating to one or more of the reactions wherein said protein kinase C-related kinases are involved under physiological conditions. The invention also relates to a process for identifying specific inhibitors for protein kinase C-related kinases. A use of such assays may not only be proposed for searching or screening purposes so as to find new substances suitable as inhibitors for PKRs, but may also be proposed for medical use, pharmaceutical or pharmacological use, food chemistry or animal food use, cosmetic testing use, etc.

Tissue-engineered silk organs
US Patent Application 20100191328
Publication Date: July 20, 2010
Assignee: Trustees of Tufts College (Medford, MA, USA)

This patent describes a lamellae tissue layer comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides a means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible.