A Green, Solvent-free Biocatalytic Method to Produce Cosmetic Esters

Jul 1, 2009 | Contact Author | By: Neil W. Boaz, PhD, and Stephanie K. Clendennen, PhD, Eastman Chemical Company
Your message has been sent.
(click to close)
Contact the Author
Save
This item has been saved to your library.
View My Library
(click to close)
Save to My Library
Title: A Green, Solvent-free Biocatalytic Method to Produce Cosmetic Esters
biocatalyticx enzymaticx greenx esterx 4-HBAx
  • Article
  • Media
  • Keywords/Abstract

Keywords: biocatalytic | enzymatic | green | ester | 4-HBA

Abstract: Cosmetic esters can be produced effectively via a solvent-free, biocatalytic method. This green process, described by the authors, involves combining two reactants and an enzyme, and is driven to high conversion by the removal of by-products through a nitrogen purge—in turn producing high purity materials directly from the reactor.

Excerpt Only This is a shortened version or summary of the article you requested. To view the complete article, please log in or create an account. Registration is Free!

Natural ingredients have always been important in the cosmetics market, and the demand for the use of greener processes is becoming more important to both formulators and consumers. In the present article-and to emphasize the distinction-natural refers to the source of raw materials, an example set by the Natural Products Association, while green refers to the process used to convert starting materials to a finished ingredient.

The US Environmental Protection Agency (EPA) has adopted a series of principles to guide the development of environmentally responsible and sustainable manufacturing, called “The 12 Principles of ‘Green’ Chemistry.”These principles have guided the development of the current biocatalytic process.

The green nature of biocatalysis- along with its mild reaction conditions, high and sometimes unique reaction selectivities, and the potential to work solvent-free-suggest that biocatalysis is a natural fit for the green preparation of cosmetic ingredients. Since petroleum-based organic solvents are undesirable for green processes, biocatalytic processes (enzymatic or microbial transformations) can instead be used since they generally are considered green.

Excerpt Only This is a shortened version or summary of the article you requested. To view the complete article, please log in or create an account. Registration is Free!

 

Close

Table 1. Tyrosinase inhibition values of skin illuminating ingredients

 Table 1. Tyrosinase inhibition values of skin illuminating ingredients

Table 2. Tyrosinase inhibition values of selected esters of 4-HBA

 Table 2. Tyrosinase inhibition values of selected esters of 4-HBA

Figure 1. Batch solvent-free biocatalytic reaction

 Figure 1. Batch solvent-free biocatalytic reaction

Figure 2. Emulsion viscosity vs. shear rate.

 Figure 2. Emulsion viscosity vs. shear rate.

Next image >