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Exposure to tin and tin salts as they occur naturally in the environment poses no significant toxicological hazard to the general public, although a potential for human sensitization has been recognized. Significant accumulation of the metal or its salts in the organism is unlikely due to their poor solubility and minimal absorption form the repiratory and GI tracts. Tin fluoride has been used for many years in toothpaste and topical solutions, but the instability of the aqueous solutions appears to be a major disadvantage.
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