Technically Speaking: From Keratin Regulation Through Wet Wipes Emulsion Literature Findings

By: Charles Fox, Independent Consultant

Posted: February 5, 2008, from the February 2008 issue of Cosmetics & Toiletries.

Skin and Skin Care
Regulating keratinous tissue: The Procter & Gamble Company has been issued a patent regarding methods for identifying materials that can help to regulate the condition of mammalian keratinous tissue. The patent describes methods for identifying materials to help regulate keratin in skin, hair or nails, and the use of said materials, such as in the preparation of cosmetic compositions.

The methods can also be used to generate data to support marketing and advertising claims, and to provide irritation or safety information. For example, the treatment of human epidermis with 0.5%, 1.0% or 2% n-acetylglucosamine was found to increase the expression of hyaluronic acid and procollagen-1 biomarkers in a dose-responsive manner, compared to the control. Both of these responses correspond to projected antiaging facial benefits.

Skin barrier cosmetics: Pola Chemical Industries discloses skin barrier cosmetics containing N-acylglutamicacid diesters, phytosterol glycosides and optional hyaluronic acid salt.

The company developed the cosmetics to complement UV-damaged skin for use during summer months. Thus, a one-week application of a makeup base containing phytosteryl/octyldodecyl/lauroyl glutamate and phytosterol glycoside to UV-induced rough skin of volunteers significantly decreased TEWL.

This is only an excerpt of the full article that appeared in Cosmetics & Toiletries, but you can purchase the full-text version.