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New in Biology (page 26 of 28)
Dec 23, 2005 | 05:57 PM CST
Novel Approaches for Molecular Biology and Skin Care Products
By: Lawrence A. Rheins, PhD, and Nicholas Benson, …
The increasing demand for performance-driven personal care products and the need to understand a product’s mechanism of action provides a scientific challenge to the industry formulator, toxicologist and expert evaluator.
Dec 23, 2005 | 05:12 PM CST
Effects of Occlusion (II): Wound Healing
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
This is the second article in a series discussing effects of occlusion on skin. (The series opened in November 2003 with a focus on percutaneous absorption.) The present article focuses on the effects of occlusive and semipermeable membranes on wound healing and summarizes related data.
Dec 23, 2005 | 04:05 PM CST
Effects of Occlusion (III): Irritant and Allergic Contact Dermatitis
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
This is the third article in a series discussing effects of occlusion on skin. Previously, we reviewed the effects of occlusion on the percutaneous absorption (C&T November 2003) and on wound healing (C&T April 2004). The present article focuses and summarizes the adverse effects of occlusion. Occlusion enhances skin hydration and increases percutaneous absorption of applied substances with exception. On the other hand, it may also increase the penetration of irritants and/or antigens entering into skin and hence may increase irritant and allergic contact dermatitis. Additionally, occlusion compromises skin barrier function by impairing passive transepidermal water loss at the application site, and hence aggravates the irritant effect of applied compounds.
Dec 23, 2005 | 03:04 PM CST
Gender and Dermatitis
By: Bobeck S. Modjtahedi, Sara P. Modjtahedi and H…
Are females more sensitive to allergens than males? If they are, is it because of something innate in female skin or because of life patterns of exposure to irritants?
Dec 13, 2005 | 11:26 PM CST
Ethnic Hair and Scalp Disorders
By: Valerie D. Callender and Cherie M. Young, Howa…
This article surveys the racial differences of hair, and then focuses on African-Americans, their hair grooming practices and how these practices relate to the common hair and scalp disorders unique to this population.
Dec 13, 2005 | 10:24 PM CST
Cosmetic Utilization of Micro Wound Healing Models
By: Hongbo Zhai and H.I. Maibach
Superficial wounds may be evaluated and treated in the cosmetic field. However, with natural wounds it is difficult to evaluate the effects of therapy upon the repair process because natural wounds may vary according to several factors, such as wound induction (physical or chemical), depth (superficial or deep), size (regular or irregular), site-to-site variability, and environmental factors (infection or not).
Dec 13, 2005 | 09:53 PM CST
Busy Signals Explain Itch from Dry Skin
By: Gil Yosipovitch, MD, and Kelly L. Barham, MD
This review of literature suggests that crosstalk between the stratum corneum and nerve fibers in the epidermis is the process by which itch is transmitted to the central nervous system. A rationale is presented for using moisturizers to reduce itch.
Dec 13, 2005 | 09:47 PM CST
Effect of Seawater Salts on Inflammatory Skin Disease
By: Ivy Lee and H.I. Maibach
Use of mineral spa water and seawater has been and continues to be a common treatment modality for inflammatory skin conditions such as psoriasis, atopic dermatitis and irritant contact dermatitis.
Dec 08, 2005 | 01:44 AM CST
Correlating Transepidermal Water Loss and Percutaneous Absorption: An Overview
By: Jackie Levin and H.I. Maibach
The extensive procedure required to measure percutaneous absorption versus transepidermal water loss (TEWL) enhances the desire to find a correlation between the 2 measurements to more easily assess skin barrier function. Experimentation investigating the correlation between TEWL and percutaneous absorption has yielded mixed findings. Yet despite the significant quantitative correlation demonstrated in some experiments, the precise qualitative relationship between percutaneous absorption and TEWL remains unsettled.
Dec 01, 2005 | 03:52 PM CST
Protecting the Genome of Skin Cells from Oxidative Stress and Photoaging
By: L. Danoux, C. Jeanmaire, V. Bardey, G. Périé, …
According to a concept proposed here, protection of nuclear DNA and mitochondrial DNA against UVB and UVA radiation can break the vicious cycle responsible for skin photoaging.