Recent in Biology (page 26 of 27)

Effects of Occlusion (II): Wound Healing

This is the second article in a series discussing effects of occlusion on skin. (The series opened in November 2003 with a focus on percutaneous absorption.) The present article focuses on the effects of occlusive and semipermeable membranes on wound healing and summarizes related data.

Effects of Occlusion (III): Irritant and Allergic Contact Dermatitis

This is the third article in a series discussing effects of occlusion on skin. Previously, we reviewed the effects of occlusion on the percutaneous absorption (C&T November 2003) and on wound healing (C&T April 2004). The present article focuses and summarizes the adverse effects of occlusion. Occlusion enhances skin hydration and increases percutaneous absorption of applied substances with exception. On the other hand, it may also increase the penetration of irritants and/or antigens entering into skin and hence may increase irritant and allergic contact dermatitis. Additionally, occlusion compromises skin barrier function by impairing passive transepidermal water loss at the application site, and hence aggravates the irritant effect of applied compounds.

Gender and Dermatitis

Are females more sensitive to allergens than males? If they are, is it because of something innate in female skin or because of life patterns of exposure to irritants?

Cosmetic Utilization of Micro Wound Healing Models

Superficial wounds may be evaluated and treated in the cosmetic field. However, with natural wounds it is difficult to evaluate the effects of therapy upon the repair process because natural wounds may vary according to several factors, such as wound induction (physical or chemical), depth (superficial or deep), size (regular or irregular), site-to-site variability, and environmental factors (infection or not).

Correlating Transepidermal Water Loss and Percutaneous Absorption: An Overview

The extensive procedure required to measure percutaneous absorption versus transepidermal water loss (TEWL) enhances the desire to find a correlation between the 2 measurements to more easily assess skin barrier function. Experimentation investigating the correlation between TEWL and percutaneous absorption has yielded mixed findings. Yet despite the significant quantitative correlation demonstrated in some experiments, the precise qualitative relationship between percutaneous absorption and TEWL remains unsettled.

Protecting the Genome of Skin Cells from Oxidative Stress and Photoaging

According to a concept proposed here, protection of nuclear DNA and mitochondrial DNA against UVB and UVA radiation can break the vicious cycle responsible for skin photoaging.

Inside the Hair: An Advanced Hair Biology Model

In this survey from the literature, various writers describe a model of the inside of a hair strand, showing a multilamellar structure of the cuticle cells, a multifibril structure of the cortex, and a variety of lipids that are thought to be major contributors to the hair’s physical properties. What exactly is hair? Simply put, the answer is that hair is protein. But this simple answer does not even begin to explain the complexity and sophistication of the hair fiber.

Cigarette Smoking and Skin Biomarkers

Some research has been documented as to the damaging effects of smoking on the skin vasculature and on oxygenation in both human and animal models.

Silver, Titanium and Zirconium: Metals in Cosmetics and Personal-Care Products

This is the fifth article in a series reviewing the metals present in personal care products.

Lead, Manganese and Mercury: Metals in Personal Care Products

This article is the fourth in a series reviewing the metals present in personal care products. Earlier installments appeared in January 1998, Toxic Potential from Metals Absorbed through the Skin (pages 33-42); March 1999, Metals in Personal-Care Products, (pages 47-56); and August 2000, Chromium, Cobalt, Copper and Iron: Metals in Personal-Care Products, (pages 52-65).

Pigmentation, Swelling and Wrinkling in the Eye Area

Product development to address concerns of pigmentation, swelling, and wrinkling in the eye area requires a basic understanding of the area's unique anatomy and skin physiology.

A Dermatologic View: Metals in Cosmetics

A dermatologic view of nickel compounds in cosmetics.

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