Recent in Biology (page 17 of 20)

Research Identifies Regulator to Start/Stop Skin Growth

A recent report from Children's Hospital Boston reveals how researchers in the Stem Cell Program have discovered a regulator of gene activity that tells epidermal stem cells when to grow more skin or that can sense cell crowding and cease the growth.

A Review of Anti-Irritants, Part I: Barrier Cream Efficacy on Contact Dermatitis*

This column is the first of a two-part series about anti-irritants. Part two will appear in the April 2011 issue. While the first part covers anti-irritants, irritant reaction and barrier cream efficacy, part two will summarize the efficacy of moisturizers and anti-irritant substances and provide an overall interpretation of both parts I and II.

Desmosomes: Adhesion Answers to Skin

Garrod became interested in cell adhesion after reading a paper on the differential adhesion hypothesis by Malcolm Steinberg, and he more recently discovered the mechanism that allows these structures to tightly bind cells together.

P. Acnes Found to Cause Infections Other Than Acne

Peter Lambert, PhD, a professor of microbiology at Aston University's school of life and health sciences, has reported that Propionibacterium acnes (P. acnes), the bacterium that causes acne, may already be present within the body and cause other infections.

Research Suggests Triclosan Exposure May Increase Allergies

A study conducted by the University of Michigan's School of Public Health suggests that individuals exposed to triclosan in personal care products may suffer from increased allergies.

Researchers Investigate Photocontact Allergy in Sunscreens

Researchers at the University of Gothenburg and Chalmers University of Technology have investigated what happens when sun care products break down in the presence of UV radiation to better understand photocontact allergy with this process.

New Findings Regarding Mechanism of Contact Nickel Allergy

Recent work published in Nature Immunology shows new findings regarding contact nickel allergy. Research from the University Hospital Mannheim and University of Heidelberg, in Germany, suggests the human Toll-like receptor 4 is crucial in the development of this skin reaction.

Capsaicin in Pain Relief Creams as a Co-carcinogen?

Researchers from the Hormel Institute at the University of Minnesota have found that capsaicin formulated in pain relief creams may promote skin cancer.

Variations in Pigmentation and Ultrastructural Skin Differences Among Ethnic Groups

As formulators create products for varying ethnic backgrounds and with diverse skin types, an understanding of differences in pigmentation and skin structure and function becomes more important. This column reviews recent studies on the structural, genetic and ultraviolet (UV)-responsive differences in skin pigmentation to allow the formulator to create successful products for varying ethnicities and to accurately measure pigmentation.

Enhancing Sunscreen Efficacy for Realistic Application

The ability of a sunscreen to protect the skin from erythema is expressed on product labels as the sunburn protection factor (SPF)—i.e., the ratio of the minimum erythema dose (MED) with sunscreen to the MED without protection. Yet in reality, consumers do not apply the same mass/cm2 as is utilized in SPF testing, so maximal protection is not achieved.

Center for Skin Sciences Established, Reports New Findings in Skin Tanning

Twenty five years after a fire claimed many lives, the Center for Skin Sciences at the University of Bradford (Bradford, UK), specializing in wound healing, was officially established to honor those who died. The occasion was marked by a symposium. In addition, the group recently announced new findings in relation to sunburn-prone skin and the potential for tanning.

Researchers Identify Physiological Sensor Important for Skin Barrier Function

Researchers at the National Institute for Physiological Sciences (NIPS) have reported that the transient receptor potential vanilloid 4 (TRPV4) ion channel in keratinocytes is important to maintain skin barrier function and prevent skin dehydation. According to these researchers, chemicals that modulate TRPV4 activity, could affect barrier repair of damaged skin.

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