Recent in Biology (page 13 of 27)

Human Skin and Ocular Flora: The Effect of Product Formulation, Part 1

This first of two articles reviews transient and resident microbial populations of the human skin and how they alter with age, environment and exposure to antimicrobial agents. Considerations for the formulator of how cosmetic products may affect and be impacted by normal human flora also are provided.

Eye Color Cosmetics and Contact Dermatitis

Following is an overview of research correlating, even at trace amounts, raw materials present in eye area color cosmetics with contact dermatitis.

Researchers Link DNA Repair Protein With Increased Skin Cancer

Researchers from the University of North Carolina at Chapel Hill have established a connection between a repairing protein and times of the day with an increased risk of skin cancer.

Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis

In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.

A Dermatological View—The Controversial Influence of Moisturizers on Skin Water Barrier

As is described here, moisturizers can influence the properties and structure of corneocytes by influencing the SC and consequently, the skin water barrier function. This hydrative influence of moisturizers could be beneficial as well as destructive toward skin barrier function.

Effects of Occlusive and Semipermeable Membranes on Wound Healing

Skin occlusion is a complex issue. Occlusion usually means the skin is covered directly or indirectly by impermeable films or substances, but certain topical vehicles that contain fats and/or polymer oils may also generate occlusive effects. They speed healing, but can also encourage the formation of bacteria. In the following excerpt, Zhai, MD, and Maibach, MD, review recent studies in various modes and methods of occlusion.

Researchers Connect FADD Protein to Skin Inflammation

Researchers from the University of Cologne, Ghent University and the German Sport University Cologne have identified the protein that may stop necroptosis in keratinocytes, thereby preventing skin inflammation.

Researchers Disprove Resistance With Antibacterial Soap Use

A collaboration of researchers have reported that use of antibacterial soaps does not lead to antibiotic or antibacterial resistance.

Defining Clinically Relevant Fragrance Allergens: The Challenge (Part I)

Contact allergic dermatitis is a common, and some say pervasive public health problem. The degree to which fragrances and fragranced products contribute to this issue is investigated in a two-part overview by Howard Maibach, MD, and Jurij Hostýnek, PhD, from which the following is excerpted.

Comparatively Speaking: Keratinocyte vs. Corneocyte

Here, industry expert Tony O'Lenick asks Kelly Dobos to explain the difference between keratinocytes and corneocytes. Many skin care products target either keratinocytes or corneocytes; therefore, understanding their differences and the basic structure of human skin is important for formulators.

Study Discovers Mechanism Behind Caffeine's Inhibition of UV-induced Cancer

Researchers at Rutgers have suggested that topical caffeine may help lower the risk of UV-induced skin cancer.

Effects of Occlusion: Irritant and Allergic Contact Dermatitis

Occlusion bears both positive and negative effects on the health and integrity of skin. In the following excerpt, Hongbo Zhai, MD, and Howard Maibach, MD, introduce a discussion of the effects of occlusion on skin.

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