What do We Know About Depigmenting Agents?

Sep 29, 2015Sparsha Saxena, Rosa Andersen, M.D., and Howard I. Maibach, M.D., University of California, San Francisco, CA

This review examines the efficacy and tolerability of agents such as hydroquinone, ascorbic acid and retinol to treat hyperpigmentation disorders. The authors assess the quality of studies as a tool to determine efficacy of depigmenting agents. Along with outcome, they also analyze study design, participant skin type, duration, intervention and statistical significance.

Olay Breakthrough Identifies Traits of ‘Ageless’ Women

Jun 17, 2015

The Multi-Decade and Ethnicity (MDE) study reveals biological commonalities among a subset of women who look exceptionally younger than their age.

Gold Microparticles Zap Sebaceous Follicles

Jun 15, 2015

Nano shells enable selective photothermolysis to help treat acne.

Shaving and its Effects on Percutaneous Absorption in the Skin*

Jun 1, 2015Muhammad Hamza, University of California, San Francisco, and Dow University of Health Sciences, Karachi, Pakistan; and Howard I. Maibach, M.D., University of California, San Francisco

Despite its being an area of concern for many years, the percutaneous absorption of cosmetics has not been rigorously studied. Additionally, the effects of shaving on this process are relatively unknown. An overview of recent research reveals that more research in this area is required.

Higher Incidence of Nonmelanoma Skin Cancer Found in Asian and Hispanic Women

Apr 10, 2015

According to a study presented at the American Academy of Dermatology’s 73rd Annual Meeting in San Francisco, Asian and Hispanic women have an increased risk of developing nonmelanoma skin cancer (NMSC).

Atopic Dermatitis—Part I: Early Research and Causes

Mar 1, 2015Rosa Marie Andersen, MD; and Howard I. Maibach, MD, University of California at San Francisco University of California at San Francisco, San Francisco, USA

This column is the first in a two-part series on atopic dermatitis (AD), a common, chronic inflammatory skin disease. Here, the authors will review early research and delve into causes of AD to support a future column on AD criteria and investigation.

Research Suggests a Need for After-sun Sunscreen

Feb 24, 2015

According to a report from Yale, the damage caused by UV radiation continues hours after the sun exposure occurred. In the described study, melanocytes generated CPDs both immediately and hours after UV exposure had ended. This may suggest the need for “evening-after” sunscreen, designed to block energy-transfer.

Researchers Link Skin Cell Molecule with Immune Response

Feb 11, 2015

Researchers from Melbourne, Monash and Harvard Universities published new findings on how immune cells in the skin sense foreign invaders and react with inflammation or alergic reactions to protect the body.

ROS Suspected to be Beneficial to Wound Healing

Jan 2, 2015

Free radicals might not be all bad, according to researchers from the University of California, San Diego. Andrew Chishold, PhD, and his fellow researchers found reactive oxygen species (ROS) to be beneficial to wound healing.

Sunscreen Across the Spectrum?

Dec 1, 2014

Newer to the scene are products that protect skin against infrared radiation, as well as research on the effects of high energy visible and visible light. In response, at the C&T Summit, Jürgen Lademann, PhD, will present "Should Sunscreens Protect Across the Whole Solar Spectrum?"

Olay Conducts Clinical Trial On Pollution's Skin Impact

Nov 19, 2014

Pollution is bad news for the skin regardless of lifestyle choices, according to a study by Olay scientists and Beijing's General Hospital of the Air Force. The two collaborated to study environmental factors and skin in a city well known for its poor air quality.

Researchers Find Fat Burning Action in Adenosine

Oct 28, 2014

Researchers from the University Hospital Bonn have reported that adenosine may stimulate brown fat to burn off undesirable white fat cells.

Skin Aging at the Functional Proteomics Level: Elastin as a Marker

Aug 25, 2014Nava Dayan, PhD, Dr. Nava Dayan LLC; and Matthew Kuruc, Biotech Support Group LLC

There is general agreement on elastin’s role in skin health, aging and appearance, but no method has yet elucidated how it degrades with aging when challenged by sun exposure or other means. This paper reviews two inconsistent theories in the literature, degradation and buildup, and highlights potential methods to marry the two. It also suggests proteomics as a method for further investigation.

An Approach to Develop Cosmetics for Multi-tonal Brazilian Skin

Aug 25, 2014Doraci Aleixo Maciel, Dilene Foggi Bet, Edilson Luiz Rocha, Flavia Bogo Ribas and Valéria Maria Di Mambro, Grupo Boticário; and Érica de Oliveira Monteiro, E.M. Dermatologia

In Brazil, people have many different colored skin tones, and women often struggle to match makeup shades to their skin color. This paper describes an exploratory study of hundreds of volunteers that was conducted to understand Brazilian women's skin color, ultimately to develop a makeup line for this widely diverse market.

Nature-derived Care for Sensitive and Difficult-to-treat Skin Types

Jul 1, 2014Katerina Steventon, PhD, FaceWorkshops, LLC

A number of consumers can be classified as having difficult-to-treat skin types, being both dry and oily and prone to periodical inflammation in specific areas. New active ingredients derived from nature provide gentle yet efficacious solutions to address these needs. These skin types and solutions are addressed herein.

Stanford Study Connects Stem Cell Protein to Human Hair Color

Jun 4, 2014

According to a study by Stanford University School of Medicine, a molecule crucial to stem cell functioning plays a major role in controlling human hair color.

Literature Review: Damage, Growth and Conditioning in Hair

May 20, 2014Rachel L. Grabenhofer, Cosmetics & Toiletries

This survey of recent literature relates to assessing hair damage, reducing dye allergy, increasing and inhibiting hair growth, cleansing and conditioning hair, and more. The papers are presented as food for thought in the early stages of the product development process, and may warrant deeper investigation.

Klotho Gene Variant Found to Enhance Cognition

May 14, 2014

According to new research from Pennsylvania State University, a variant of the Klotho gene, which relates to lifespan, has been connected with improved cognitive functioning. This pathway has been the focus of recent anti-aging research for cosmetics.

Molecular Biology in Future Skin and Hair Care

May 1, 2014Howard Epstein, PhD, EMD Chemicals, Philadelphia, USA

Techniques developed in the field of molecular biology are currently being used to screen cosmeceutical ingredients for skin and hair care applications. New findings are published on a daily basis, providing insight with respect to future innovations for skin and hair health and appearance. Several relevant developments are reviewed here.

Shiseido to Open Center for Hair Regeneration Research

Apr 20, 2014

The Shiseido Cell-Processing and Expansion Center (SPEC) is set to open on May 1, 2014, and will centralize the research and development of regenerative hair treatments.

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