Recent in Biology (page 12 of 14)

A Dermatological View—Interpreting Placebo Response in Clinical Trials for Psoriasis

By comparing response rates of placebo versus active drug groups in psoriasis RCTs evaluating biologic agents, the authors of this column sought to clarify factors contributing to placebo responses and their implications in improving clinical trial design to determine more accurate drug efficacies.

A Dermatological View—Scalp Irritation From Hair Care Chemicals

While scalp irritation also can be caused by contact with physical or biological agents, this column will discuss the irritation resulting from hair chemicals. The desire for a specific hairstyle or color can render the scalp exposed to different hair chemicals that may result to scalp irritation.

Eccrine Sweat Glands Identified Key in Wound Healing

Researchers from the University of Michigan, Ann Arbor have reported that eccrine sweat glands may play a role in wound healing. The researchers believe this understanding could lead to improved wound treatments.

Sea Cucumber Peptides to Affect Collagen

Sea cucumbers, considered a delicacy in East and Southeast Asia, may not be pleasing to the eye but could be pleasing to the complexion. These slippery creatures belong to the animal group of echinoderms, which possess an adaptive feature called mutable connective tissue. While investigating this phenomenon, Maurice Elphick, PhD, and his research team from Queen Mary University of London’s School of Biological and Chemical Sciences not only identified the genes that encode the peptides to make this tissue stiffen and soften, but also have hypothesized that one of these peptides may be used in anti-aging skin care

A Dermatological View—Moisturizers: Evidence for Efficacy

Despite their widespread use and applications, the scientific literature on moisturizers lacks strong evidence to support dermatological use. This article explores current literature on the efficacy of moisturizers to help the industry understand their mechanisms and role in treatment.

Characterizing and Evaluating the Effectiveness of Volcanic Pumice Exfoliants

Pumice has a recognized application­­­­ as an abrasive agent to promote exfoliation of the skin. In this study, different particle size fractions of pumice sampled from several geologic occurrences in São Miguel’s island, the Azores archipelago, were used in the preparation of exfoliation formulations. Gels and soap were prepared and characterized, and their efficacy evaluated.

In Sight—UVA Protection Through Strawberry Anthocyanins

Scientists at the Università Politecnica delle Marche, The University of Barcelona, the University of Salamanca and the University of Granada have produced an extract of strawberry to quantify the ability of the fruit to protect the skin.

A Dermatological View—Percutaneous Penetration of Amino Acids

Skin care products containing amino acids often promote the benefits conferred on the skin by these molecules. Natural amino acids found in the skin have been found to improve the health of skin through antioxidation, membrane stabilization and increasing skin’s natural moisturizing factor (NMF).

Comparatively Speaking: Gram-positive vs. Gram-negative Bacteria

Tony O’Lenick asks industry expert Kelly Dobos to explain the difference between Gram-negative and Gram-positive bacteria to understand the importance of selecting the proper preservative system for a cosmetic.

A Review of Skin Hypopigmentation and Contemporary Strategies to Achieve an Even Skin Tone

Whether formulating for Asia, North America, Europe or Latin America, the cosmetic chemist will face one common demand in all these markets: an even skin tone. This article provides an overview of chemical and biological agents capable of causing hypopigmentation via interactions through different stages of the melanogenic pathway.

Comparatively Speaking: Pathogenic vs. Non-pathogenic Bacteria

To explain the difference between pathogenic and nonpathogenic bacteria, Tony O’Lenick looks to Kelly Dobos, who notes that nonpathogenic bacteria could become pathogens in immune-compromised hosts.

In Sight—Nano-sizing Chitosan for Wound Healing, Anti-aging

Mihaela Leonida, PhD, a professor of chemistry at Fairleigh Dickinson University, investigated the antibacterial properties of chitosan for cosmetic and pharmaceutical uses. She found that the material exhibited enhanced effects after being nano-sized.

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