Recent in Biology (page 10 of 27)

A Dermatological View—Interpreting Placebo Response in Clinical Trials for Psoriasis

By comparing response rates of placebo versus active drug groups in psoriasis RCTs evaluating biologic agents, the authors of this column sought to clarify factors contributing to placebo responses and their implications in improving clinical trial design to determine more accurate drug efficacies.

UVA Protection Through Strawberry Anthocyanins

Scientists at the Università Politecnica delle Marche, The University of Barcelona, the University of Salamanca and the University of Granada have produced an extract of strawberry to quantify the ability of the fruit to protect the skin.

Nano-sizing Chitosan for Wound Healing, Anti-aging

Mihaela Leonida, PhD, a professor of chemistry at Fairleigh Dickinson University, investigated the antibacterial properties of chitosan for cosmetic and pharmaceutical uses. She found that the material exhibited enhanced effects after being nano-sized.

Consumer Perspective—Skin Types and Sensory Experience

Sophisticated texture and fragrance as part of a formulation’s aesthetics are important to the discerning consumer, and skin type is the primary influence behind how the consumer perceives a skin care product. For example, consumers with dry skin require a richer moisturizer, even though the product should absorb quickly for a smooth finish.

A Dermatological View—Innovations in Hyaluronic Acid

HA is critically important to dermatologists and to cosmetic scientists, as it maintains the moisture in skin, and loss of accessible HA results in wrinkling and changes associated with aging. Replacement of such HA is the goal of many cosmetic and cosmeceutical techniques and reagents.

New Skin Research from Beiersdorf Tracks Skin Chonology

In a collaboration with researchers at Charité University Medicine Berlin, Beiersdorf scientists were able to demonstrate the existence of an inner clock in human skin cells, which controls skin regeneration among other things.

Penetration of Cosmetics Into and Through the Stratum Corneum

The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.

A Dermatological View—Interpreting Placebo Response in Clinical Trials for Psoriasis

By comparing response rates of placebo versus active drug groups in psoriasis RCTs evaluating biologic agents, the authors of this column sought to clarify factors contributing to placebo responses and their implications in improving clinical trial design to determine more accurate drug efficacies.

A Dermatological View—Scalp Irritation From Hair Care Chemicals

While scalp irritation also can be caused by contact with physical or biological agents, this column will discuss the irritation resulting from hair chemicals. The desire for a specific hairstyle or color can render the scalp exposed to different hair chemicals that may result to scalp irritation.

Eccrine Sweat Glands Identified Key in Wound Healing

Researchers from the University of Michigan, Ann Arbor have reported that eccrine sweat glands may play a role in wound healing. The researchers believe this understanding could lead to improved wound treatments.

Sea Cucumber Peptides to Affect Collagen

Sea cucumbers, considered a delicacy in East and Southeast Asia, may not be pleasing to the eye but could be pleasing to the complexion. These slippery creatures belong to the animal group of echinoderms, which possess an adaptive feature called mutable connective tissue. While investigating this phenomenon, Maurice Elphick, PhD, and his research team from Queen Mary University of London’s School of Biological and Chemical Sciences not only identified the genes that encode the peptides to make this tissue stiffen and soften, but also have hypothesized that one of these peptides may be used in anti-aging skin care

A Dermatological View—Moisturizers: Evidence for Efficacy

Despite their widespread use and applications, the scientific literature on moisturizers lacks strong evidence to support dermatological use. This article explores current literature on the efficacy of moisturizers to help the industry understand their mechanisms and role in treatment.

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