In Sight: Stimulating Stem Cells for Younger Skin

By: Katie Schaefer, Cosmetics & Toiletries magazine

Posted: November 2, 2007, from the November 2007 issue of Cosmetics & Toiletries.

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“When the product stimulates these markers, you get a popcorn effect; once a couple are rejuvenated, more and more are rejuvenated,” said Rinaldi.

Highlighting stem cell markers boosts cellular renewal, according to Rinaldi, thereby reducing the appearance of wrinkles and the discoloration associated with photoaging.

After the product was tested in vitro for its activity on stem cells, it was tested in vivo by performing biopsies both before and after application of the product.

Although polypeptide 153 is the chief ingredient in the serum, additional ingredients are reported to help increase the product’s antiaging benefits. Among them are hydrolyzed soy extract to visibly reduce the appearance of wrinkles, a smaller peptide to reduce the appearance of forehead wrinkles, and Scotch pine extract to reduce hyperpigmentation and blotchiness.

According to Rinaldi, the company plans to expand its use of polypeptide 153 from just a face emulsion to a whole line of products for the neck, décolleté, eyes and body. Some have questioned the appropriateness of utilizing the technology for a cosmetic product but Rinaldi finds the usage completely appropriate.