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Ingredient Review Update from CTFA
Posted: April 22, 2006
page 2 of 4
Tentative Safety Assessments
Interested persons are given 90 days to comment, provide information, and/or request an oral hearing before the CIR expert panel regarding tentative safety assessments. Information may be submitted without identifying the source or the trade name of the cosmetic product containing the ingredient. All unpublished data submitted to CIR will be discussed in open meetings and are available at the CIR office for review by any interested party. Data submissions are requested by July 6, 2006. These ingredient reports are next scheduled for review by the CIR Expert Panel at its August 14-15, 2006 meeting. Tentative safety assessments are available from the CIR.
2-amino-3-nitrophenol; 2-amino-4-nitrophenol; 2-amino-4-nitrophenol sulfate; 2-amino-5-nitrophenol; 4-amino-2-nitrophenol; 4-amino-3-nitrophenol; 3-nitro-p-hydroxyethylaminophenol; and 4-hydroxypropylamino-3-nitrophenol were deemed safe as hair dye ingredients in the practices of use and concentration as described in the safety assessment; except that the available data are insufficient to support the safety of 4-Amino-2-nitrophenol as a hair dye ingredient.
Polyisobutene and hydrogenated polyisobutene were determined to be safe as cosmetic ingredients in the practices of use and concentration as described in the safety assessment.