Wrinkle Reduction by Stimulation of the Skin’s Mechanical Resistance

November 1, 2006 | Contact Author | By: Catherine Lenaers, David Boudier, Christa Chauprade, Delphine Rondeau and Brigitte Closs, Silab
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Title: Wrinkle Reduction by Stimulation of the Skin’s Mechanical Resistance
antiagingx skin mechanical resistancex mechano-receptorx integrinx vinculinx alpha-smooth muscle actinx
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Keywords: antiaging | skin mechanical resistance | mechano-receptor | integrin | vinculin | alpha-smooth muscle actin

Abstract: A rye extract rich in arabinoxylans is shown to stimulate the synthesis of mechano-receptor proteins and alpha-SMA fibers in the skin, improving the skin’s mechanical resistance and reducing the appearance of gravity wrinkles.

Wrinkles are a symptom of structural failure in the dermis. They indicate that the skin is losing its ability to support its own weight, and that fibroblasts in the dermis are losing their capacity to attach to collagen fibers and transmit mechanical information.

The capacity of the skin to adapt to mechanical stresses, or cell mechanics, can be considered as a new approach to the fight against the signs of aging, especially those of chronobiological aging.

This article reports on an arabinoxylans-rich rye extract that stimulates the skin’s own lifting properties and boosts the mechanical resistance of the dermis.