Natural Preservation from Concepts in Nature

Mar 1, 2008 | Contact Author | By: Fernando Ibarra, PhD, Dr. Straetmans GmbH and Christopher H. Johnson, Kinetik Technologies Inc.
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Title: Natural Preservation from Concepts in Nature
preservationx natural antimicrobialsx organic acidsx glyceryl monoestersx
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Keywords: preservation | natural antimicrobials | organic acids | glyceryl monoesters

Abstract: Chemical defense mechanisms used in the plant kingdom are the basis of natural antimicrobials with multifunctionality for preservation of cosmetic formulations. Two examples are organic acids and glyceryl monoesters.

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Nature demonstrates various protective strategies in the animal and plant kingdom. At the macroscopic scale, mobility (i.e., the ability to run) is the first and most obvious example, but slow or immobile creatures have evolved other fascinating ways to protect themselves. Chemical strategies can play an important role in this context. Strong odors and bright colors are often employed to point out that an attack may bring more harm to the aggressor than to the prey. This strategy depends on the large variety of naturally toxic materials produced by animals and plants in their “natural laboratories” in which some of the world’s most effective poisons are developed. Figure 1 gives the structures of some exemplary natural poisons.

Somewhat more hidden and therefore less known are the activities in the microscopic world. The strategy for chemical defense against microorganisms will normally differ from that against larger invaders due, in part, to differences in the metabolism. While large alkaloids or polypeptides may successfully harm animals, it is sometimes small and simple molecules that are effective against bacteria or fungi. Chemical defense against microbes is normally found in plants or other competing microorganisms, while animals rely on their biological immune response.

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Table 1. Comparison of MIC values

 Table 1. Comparison of MIC values

Petrochemical Preservatives and The Term Natural

 Petrochemical Preservatives and The Term Natural

Figure 1. Structures

 Figure 1. Structures

Figure 2. Antimicrobial mode

 Figure 2. Antimicrobial mode

Figure 3. Results of challenge test

 Figure 3. Results of challenge test

Figure 4. Disruption of the cell membrane

 Figure 4. Disruption of the cell membrane 

Figure 5. Results of challenge test

 Figure 5. Results of challenge test

Natural Preservation footnote

a Dermosoft is a product line and registered trade name of Dr. Straetmans Chemische Produkte GmbH, Germany. 

Formula 1. Moisture cream preserved with organic acids

 Formula 1. Moisture cream preserved with organic acids

Formula 2. Body spray preserved with glyceryl monoesters

 Formula 2. Body spray preserved with glyceryl monoesters

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