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Delivery

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Researchers Develop 'Dendrimersomes' for Cosmetic Delivery

Posted: May 24, 2010

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According to the report, dendrimersomes are capable of incorporating pore-forming proteins, can assemble with structure-directing phospholipids and block copolymers, and offer a molecular periphery suitable for chemical functionalization without affecting their self-assembly.

While liposomes mimic cell membranes assembled from natural phospholipids or from synthetic amphiphiles, liposomes reportedly are not stable and vary widely in size, requiring stabilization and fractionation for all practical applications. Conversely, polymersomes are stable but polydisperse, and most are not biocompatible, requiring scientific intervention to combine the best properties of both for nanomedicine.

The benefits of this work for personal care are relevant for skin delivery and could provide personal care formulators with a new means of increased efficacy while requiring less active.