Patent Picks—Methyl Naphthalenyl Ketone, Oxylipins, Metal Oxide Shell Microcapsules, Tsuga, Furanone and More for the Treatment of Skin Inflammation and Irritation

Jul 26, 2011 | Contact Author | By: Katie Anderson (Schaefer), Cosmetics & Toiletries magazine
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Title: Patent Picks—Methyl Naphthalenyl Ketone, Oxylipins, Metal Oxide Shell Microcapsules, Tsuga, Furanone and More for the Treatment of Skin Inflammation and Irritation
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Wet wipe lotions comprising particulate material
United States Patent 7977301
Publication Date: July 12, 2011
Assignee: The Procter & Gamble Company

The present invention provides a wet wipe made up of a substrate impregnated with a cleaning lotion where the cleaning lotion includes a particulate material. A wet wipe comprising a substrate may impregnated with a cleaning lotion. The cleaning lotion may comprise an emollient, a surface active material, a rheology modifier and water. The cleaning lotion may further comprise a particulate material at a concentration less than about 2.5%. The cleaning lotion may have: a viscosity less than about 100 centipoise at a shear stress of 10 Pa; and a viscosity greater than about 4000 centipoise at a shear stress of 0.05 Pa. The cleaning lotion may further have a yield value at a shear stress greater than 0.05 Pa.

Wet wipes, which can also be referred to as “pre-moistened wipes” and “towelettes”, are suitable for use in cleaning babies, and can also find use in cleaning tasks related to persons of all ages. Such wipes can also include articles used for application and removal of substances to the body, including but not limited to application and removal of makeup, skin conditioners, ointments, sunscreens, insect repellents and medications.

Use of at Least One Extract of Flowers of Camellia Japonica Alba Plena for Moisturizing the Skin
WIPO Patent Application WO/2011/083110
Publication Date: July 14, 2011
Assignee: Chanel Parfume Beaute, Y Maestro and C Lasserre

The present invention relates to a cosmetic composition containing an extract of flowers of Camellia Japonica Alba Plena, as well as the cosmetic use thereof, for moisturizing and/or protecting human skin against drying. It also relates to an extract of flowers of Camellia Japonica Alba Plena, characterized in that it can be obtained by extraction of flowers by means of at least one alcoholic solvent.

Method for treating an inflammation or lesion caused by a virus
US Patent 7981933
Publication Date: July 19, 2011
Assignee: Life Force Technologies LLC

A method for treating an inflammation or lesion caused by herpes virus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust the pH of the composition to below 4.6.

Topical administration of the composition is preferred and is effective in treating lesions associated infections by viruses such as herpes simplex. Nasal deliverable forms are effective in treating symptoms due to viruses that cause the common cold. Pharmaceutical compositions for use in the present method are provided.

Personal Care Compositiongs Comprising Methyl Naphthalenyl Ketone or a Derivative Thereof
WIPO Patent Application WO/2011/088073
Publication Date: July 21, 2011
Assignee: The Gillette Company, KA Bakes,TW Coffindaffer, JC Haught, HR Kemp, Y Lin and T Sreekrishna

Disclosed is a personal care composition comprising a methyl naphthalenyl ketone or a derivative thereof, such as 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2naphthalenyl)-ethan-1-one, for down regulating at least one TRP receptor associated with a pain response, including but not limited to TRPV1 and TRPA1 receptors to reduce skin irritation associated with hair removal.

Sexual Hygienic Composition
US Patent Application 20110178488
Publication Date: July 21, 2011
Assignee: Dolhay Klinika Egeszsegugyi KFT

The invention is a sexual hygienic preparation comprising extract prepared from the milk of at least one equid animal. The preparation may contain medically/therapeutically acceptable additive(s) in specified cases. The preparation is formulated preferably as a feminine cleansing gel, feminine cleansing shampoo, feminine cleansing soap, vaginal suppository, vaginal pill, vaginal cleansing liquid, concentrate, water-soluble solid vaginal cleansing preparation, effervescent tablet, granulate, powder, lyophylized Lactobacillus preparation, spermicide preparation; adsorbent material such as dry or wet wipe, sanitary pad, vaginal suppository, containing sexual hygienic preparation.

Avermectin/Hydrocortisone Composition fro Treating Afflictions of the Skin, e.g. Rosacea
US Patent Application 20110178049
Publication Date: July 21, 2011
Assignee: Galderma S.A. (Cham, CH),

Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and hydrocortisone or salt, ester or derivative thereof, are useful for treating afflictions of the skin, especially rosacea.

Oxylipins From Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same
US Patent Application 20110178047
Publication Date: July 21, 2011
Assignee: Martek Biosciences Corp.

Disclosed are novel oxylipins, referred to herein as docosanoids, that are derived from C22 polyunsaturated fatty acids, and method of making and using such oxylipins. Also disclosed is the use of docosapentaenoic acid (C22:5n-6) (DPAn-6), docosapentaenoic acid (C22:5n-3) (DPAn-3), and docosatetraenoic acid (DTAn-6: C22:4n-6) as substrates for the production of novel oxylipins, and to the oxylipins produced thereby. Also disclosed is the use of DPAn-6, DPAn-3, DTAn-6, and/or the oxylipins derived therefrom, and/or novel docosanoids derived from the structures of C22 fatty acids, in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. The invention also relates to novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of LCPUFA-derived oxylipins, and particularly, docosanoids.

Microcapsules Comprising Active Ingredients and Metal Oxide Shell, A Method for Their Preparation and Uses Thereof
US Patent Application 20110177951
Publication Date: July 21, 2011
Assignee: Sol-Gel Technologies Ltd.

The present invention relates to a process for preparing microcapsules comprising a core material encapsulated by a metal oxide shell, said process comprising: (a) preparing an o/w emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) including metal oxide nanoparticles in said aqueous phase either prior, during or after (a); and (c) applying conditions to obtain microcapsules.

The invention further relates to microcapsules obtainable by the process as described in the present invention. The invention additionally relates to microcapsules comprising a core material encapsulated by a metal oxide shell, wherein said core material is (i) a liquid or (ii) a dispersion in liquid; wherein the thickness of said shell is in the range 0.1-10 micron; and wherein said shell is obtained from (a) metal oxide nanoparticles, and (b) a hydrolyzed and polymerized sol gel precursor. Moreover, the invention relates to a composition comprising microcapsules as described in the present invention; and a carrier. The invention additionally relates to a method for treating a surface condition in a subject, comprising topically administering onto the surface a composition as described in the invention, wherein the core material comprises a topically acting active agent.

The invention further relates to a composition comprising microcapsules as described in the present invention, wherein the core material comprises a topically acting active agent, for treatment of a disease or disorder selected from acne, infection, inflammation, puritis, psoriasis, seborrhea, contact dermatitis, rosasea, and a combination thereof. Moreover, the invention relates to use of microcapsules as described in the present invention, wherein the core material comprises a topically acting active agent for the preparation of a medicament for topical administration on the skin or mucosal membrane. Additionally, the invention relates to compositions for pest control comprising microcapsules as described in the present invention, wherein said core material comprises a pesticide.

Extracts from Plants of the Tsuga Genus and Uses Thereof in the Treatment of Inflammation, Irritation and/or Infection
US Patent Application 20110177014
Publication Date: July 21, 2011
Assignee: Biopharmacopae Design International Inc.

Provided are extracts from plants of the Tsuga genus that have anti-inflammatory and anti-microbial properties. The Tsuga extracts are suitable for the treatment of inflammation, irritation and/or infection. For example, for the treatment of dermatological conditions with an associated inflammatory component or infection; for combating the irritant or inflammatory effects of other skin treatment compounds; for combating the irritant or inflammatory effects of environmental factors; for treating obesity-related skin problems (for example, inflammation, redness, erythema, rashes and/or bacterial infections caused by skin folds); for combating the irritant or inflammatory effects of, or infection due to, exfoliation, laser treatments or hair removal; for treating irritation, inflammation and/or infection associated with diaper rash; for incorporation into dermatological formulations for sensitive skins, and for providing a preservative effect to dermatological formulations, as well as for ameliorating the dermatological effects of aging.

Furanone derivatives
United States Patent 7985771
Publication Date: July 26, 2011
Assignee: Monsanto Technology LLC

The invention relates furanone derivatives and the pharmaceutically acceptable salts thereof for treating one or more conditions of the skin, in particular regulating skin condition, regulating signs of skin aging, treating a number of conditions such as contact dermatitis, skin irritation, rosacea, acne, psoriasis, and preventing and protecting skin tissue against age-related damage or damage resulting from insults such as harmful (UV) radiation or environmental pollution, stress and fatigue.

The compounds of the present invention are useful for the treatment of dermatological conditions, particularly the compounds, formulation and methods of the present invention are useful in regulating skin condition, regulating signs of skin aging and in treating a number of conditions, including but not limited to contact dermatitis, skin irritation, rosacea, acne, psoriasis, and in the prevention and protection of skin tissue against age-related damage or damage resulting from insults such as harmful (UV) radiation or environmental pollution, stress and fatigue.

The present invention is concerned with novel furanone derivatives that are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. Such furanone derivatives are useful in the manufacture of pharmaceutical compositions for treating a number of conditions characterized by oxidative stress, and particularly, in providing neuroprotection in the event of cerebral ischemia, even when administered a significant time interval after an ischemic insult.