Recent in Active (page 7 of 14)

Inhibiting Cathepsin G to Protect Against Photoaging and Infra’aging

Ultraviolet and infrared exposure are sources of premature skin aging, characterized by solar elastosis and extracellular matrix degradation. Polygonum aviculare extract is a cathepsin G inhibitor, and is shown here to oppose photoaging and infra’aging by improving skin firmness and elasticity, in turn reducing the appearance of wrinkles.

Part II: The Clinical Effects of a Natural Dipeptide on the Biological Cascade

The peptide N-Acetyl-Tyr-Arg-Hexadecylester (NATAH), found in Part I to stimulate the production of elastic fibers in vitro, was next tested in vivo for its capacity to improve skin elasticity parameters, using various biophysical and imaging techniques. Significant differences in facial ptosis and extensibility were observed in the 56-day, vehicle-controlled clinical study described here.

Lucas Meyer Touts Breast-enhancing Effects of Encapsulated Ornithine

Lucas Meyer Cosmetics has introduced the breast-firming and enhancing effects of an ornithine amino acid encapsulated in its lonosome delivery system.

3-O-Ethyl Ascorbic Acid: A Stable, Vitamin C-Derived Agent for Skin Whitening

Melanin-reducing agents are considered safer alternatives to melanocytotoxic compounds. Thus, the present work examines the effects of 3-O-ethyl ascorbic acid on enhancing skin tone by reducing melanin through the inhibition of tyrosinase-related proteins. Described studies include tyrosinase and TRP-2 inhibition, in vitro and ex vivo melanin inhibition, clinical whitening, DNA protection and collagen synthesis.

Inhibiting Cathepsin G to Protect Against Photoaging and Infra’aging

Ultraviolet and infrared exposure are sources of premature skin aging, characterized by solar elastosis and extracellular matrix degradation. Polygonum aviculare extract is a cathepsin G inhibitor, and is shown here to oppose photoaging and infra’aging by improving skin firmness and elasticity, in turn reducing the appearance of wrinkles.

Induchem Activates Opioid Receptors for Anti-aging

Induchem has created an anti-aging active that maintains and activates opioid receptors in the skin to regulate cell differentiation, migration and proliferation.

Treating Wrinkles with Dimethylaminoethanol, Retinol and Mineral Salts

A placebo-controlled study was conducted to determine if the appearance of wrinkles on facial skin could be improved by a combination of three cosmetic ingredients: dimethylaminoethanol, retinol and mineral salts. Both clinical assessment and video analysis of cutaneous replicas showed a significant improvement of the wrinkle appearance.

Treating Wrinkles with Dimethylaminoethanol, Retinol and Mineral Salts

A placebo-controlled study was conducted to determine if the appearance of wrinkles on facial skin could be improved by a combination of three cosmetic ingredients: dimethylaminoethanol, retinol and mineral salts. Both clinical assessment and video analysis of cutaneous replicas showed a significant improvement of the wrinkle appearance.

TFChem's Skin Lighteners Found Non-sensitizing

Sirona Biochem Corp. has announced that the skin lightening compounds manufactured by its subsidiary TFChem, TF-849 and TFC-723, were found not to be skin sensitizers.

Formulating with Naturals—Anti-aging Actives

To provide consumers an anti-aging benefit, finished products and ingredients must ameliorate both firmness and lines and wrinkles. The loss of firmness, attributed primarily to the loss of underlying dermal support, is both a sign of skin aging and a cause of most lines and wrinkles. Thus, improving this underlying matrix to enhance skin’s appearance should be a key feature of anti-aging product performance.

Coffea bengalensis for Antiwrinkle and Skin Toning Applications

Coffea species have been widely evaluated for effects including oxidative stress protection and immunomodulation. The present study therefore evaluates the cosmetic activity of an extract obtained from cultured Coffea bengalensis stem cells. Results showed the extract imparted hydration activity in the keratinocytes, stimulated collagen synthesis in the fibroblasts and enhanced adipocyte differentiation starting from mesenchymal precursor cells.

Lightening and Illuminating Skin With Acetylated Hydroxystilbenes From Rheum rhaponticum

Skin discoloration and excessive pigmentation due to increased melanin production is associated with skin inflammation and aging. Therefore, an extract rich in acetylated hydroxystilbenes from Rheum rhaponticum was combined with panthenyl triacetate to test in the melanogenesis pathway. The complex strongly reduced melanogenesis and melanin accumulation in human skin explants, decreased melanin content in pigmented spots, increased skin brightness and enhanced skin radiance on the face of human volunteers in a double-blind clinical study.

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