Recent in Active (page 7 of 9)

TFChem's Skin Lighteners Found Non-sensitizing

Sirona Biochem Corp. has announced that the skin lightening compounds manufactured by its subsidiary TFChem, TF-849 and TFC-723, were found not to be skin sensitizers.

Formulating with Naturals—Anti-aging Actives

To provide consumers an anti-aging benefit, finished products and ingredients must ameliorate both firmness and lines and wrinkles. The loss of firmness, attributed primarily to the loss of underlying dermal support, is both a sign of skin aging and a cause of most lines and wrinkles. Thus, improving this underlying matrix to enhance skin’s appearance should be a key feature of anti-aging product performance.

Coffea bengalensis for Antiwrinkle and Skin Toning Applications

Coffea species have been widely evaluated for effects including oxidative stress protection and immunomodulation. The present study therefore evaluates the cosmetic activity of an extract obtained from cultured Coffea bengalensis stem cells. Results showed the extract imparted hydration activity in the keratinocytes, stimulated collagen synthesis in the fibroblasts and enhanced adipocyte differentiation starting from mesenchymal precursor cells.

Lightening and Illuminating Skin With Acetylated Hydroxystilbenes From Rheum rhaponticum

Skin discoloration and excessive pigmentation due to increased melanin production is associated with skin inflammation and aging. Therefore, an extract rich in acetylated hydroxystilbenes from Rheum rhaponticum was combined with panthenyl triacetate to test in the melanogenesis pathway. The complex strongly reduced melanogenesis and melanin accumulation in human skin explants, decreased melanin content in pigmented spots, increased skin brightness and enhanced skin radiance on the face of human volunteers in a double-blind clinical study.

Profile of Ascorbic Acid

L-Ascorbic acid (AscA), more commonly referred to as vitamin C, is best known for its vital role in human health and nutrition, where it functions as a cofactor in enzymatic reactions, such as collagen synthesis, and as an antioxidant.

Tetrapeptide Targets Epidermis Cohesion

Most antiaging products claim to act on the dermis; however, the epidermis, a key element of cutaneous aging, is often forgotten. In the present study, researchers selected an acetylated tetrapeptide for its effect on epidermis cohesion, triggered by activity on syndecan-1 and collagen XVII; these effects are confirmed in vivo.

Grapefruit Extract Cream: Effects on Melanin in Skin

The current work aimed to formulate a stable w/o emulsion containing grapefruit extract by entrapping the extract in the inner aqueous phase. The final formula was found to have skin-whitening, moisturizing, cleansing and antiwrinkle effects, among others.

A Direct Connection to Melanocytes

An academic study of the pathway of UV-induced pigmentation may have created a safe tan for sunseekers. Scientists at the Dana-Farber Cancer Institute, Harvard Medical School, have begun research and evaluation of the compound forskolin, which they believe darkens skin pigmentation successfully without the use of self-tanners and without sun exposure.

Cellulite: Evolving Technologies to Fight the 'Orange Peel' Battle

This article focuses on the structure of cellulite and examines materials that claim to affect its appearance via mechanisms such as lipolysis, lipogenesis, water drainage, tissue repair and the firming of skin.

Pisum Sativum Extract for Safe- and Self-Tanning

The cosmetic industry is challenged to develop active ingredients to provide the skin with a natural, healthy glow without sunlight exposure. Here, the author examines the effects of Pisum sativum extract on melanocytes and shows a time- and dose-dependent increase in skin tone, also suggesting the material could protect skin from UV damage.

Leucojum aestivum Bulb Extract for Antiaging Benefits

Dormant Leucojum aestivum bulb extract is shown by the author to provide antiaging benefits including: slowing the proliferation of melanocytes and keratinocytes potentially to reduce age spots and slow cellular aging; reducing wrinkle formation by inhibiting muscle cell contractions; and increasing SOD expression in the skin to boost its natural defenses.

Profile of Salicylic Acid

2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.