Recent in Active (page 6 of 31)

Seppic Unveils Lipoamino Acid Whitening Booster for Japanese Market

Seppic has created a skin whitening booster specifially to comply with quasi-drug (QD) regulations in Japan.

Silab Introduces Milk Thistle for Slimming/Anti-cellulite Effect

Silab has introduced a milk thistle extract designed to produce a slimming and anti-cellulite effect.

Narcissus Tazetta and Schizandra Chinensis to Regulate ‘Youth Gene Clusters’—An In vitro Analysis

A blend of Narcissus tazetta bulb and Schizandra chinensis fruit extracts was developed for anti-aging benefits and tested for efficacy on a human skin equivalent. Results indicate it regulates the functions of youth gene clusters by increasing the activities found in younger skin and reducing the activities found in aging skin specific to structure, hydration, cellular proliferation and pigmentation.

Hydrophobic α-Ketoglutarate for Increased Collagen Production

A novel mechanism to increase collagen production based on improved hydroxylation of the collagen fiber is described here. In relation, the effects of a hydrophobic derivative of a-ketoglutarate on this mechanism are examined, and results indicate increases in collagen production in senescent fibroblasts in vitro. In vivo, a significant reduction in wrinkles and improvement in elasticity were observed.

Hydrophobic α-Ketoglutarate for Increased Collagen Production

A novel mechanism to increase collagen production based on improved hydroxylation of the collagen fiber is described here. In relation, the effects of a hydrophobic derivative of a-ketoglutarate on this mechanism are examined, and results indicate increases in collagen production in senescent fibroblasts in vitro. In vivo, a significant reduction in wrinkles and improvement in elasticity were observed.

Merck Launches Self-tanning and Lightening Actives

Merck has added two new actives to its RonaCare brand of cosmetic ingredients—one for self-tanning without UV exposure and one to lighten and illuminate the skin.

3-O-Ethyl Ascorbic Acid: A Stable, Vitamin C-Derived Agent for Skin Whitening

Melanin-reducing agents are considered safer alternatives to melanocytotoxic compounds. Thus, the present work examines the effects of 3-O-ethyl ascorbic acid on enhancing skin tone by reducing melanin through the inhibition of tyrosinase-related proteins. Described studies include tyrosinase and TRP-2 inhibition, in vitro and ex vivo melanin inhibition, clinical whitening, DNA protection and collagen synthesis.

Inhibiting Cathepsin G to Protect Against Photoaging and Infra’aging

Ultraviolet and infrared exposure are sources of premature skin aging, characterized by solar elastosis and extracellular matrix degradation. Polygonum aviculare extract is a cathepsin G inhibitor, and is shown here to oppose photoaging and infra’aging by improving skin firmness and elasticity, in turn reducing the appearance of wrinkles.

Part II: The Clinical Effects of a Natural Dipeptide on the Biological Cascade

The peptide N-Acetyl-Tyr-Arg-Hexadecylester (NATAH), found in Part I to stimulate the production of elastic fibers in vitro, was next tested in vivo for its capacity to improve skin elasticity parameters, using various biophysical and imaging techniques. Significant differences in facial ptosis and extensibility were observed in the 56-day, vehicle-controlled clinical study described here.

Lucas Meyer Touts Breast-enhancing Effects of Encapsulated Ornithine

Lucas Meyer Cosmetics has introduced the breast-firming and enhancing effects of an ornithine amino acid encapsulated in its lonosome delivery system.

3-O-Ethyl Ascorbic Acid: A Stable, Vitamin C-Derived Agent for Skin Whitening

Melanin-reducing agents are considered safer alternatives to melanocytotoxic compounds. Thus, the present work examines the effects of 3-O-ethyl ascorbic acid on enhancing skin tone by reducing melanin through the inhibition of tyrosinase-related proteins. Described studies include tyrosinase and TRP-2 inhibition, in vitro and ex vivo melanin inhibition, clinical whitening, DNA protection and collagen synthesis.

Inhibiting Cathepsin G to Protect Against Photoaging and Infra’aging

Ultraviolet and infrared exposure are sources of premature skin aging, characterized by solar elastosis and extracellular matrix degradation. Polygonum aviculare extract is a cathepsin G inhibitor, and is shown here to oppose photoaging and infra’aging by improving skin firmness and elasticity, in turn reducing the appearance of wrinkles.

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