Heat- and UV-Stable Cosmetic Enzymes from Deep Sea Bacteria

May 6, 2003 | Contact Author | By: Claire mas-Chamberlin, Fracois Lamy, Philippe Mondon, Sebastien Scocci, Laurent de Givry, Francois Vissac and Karl Lintner, Sederma; Lawrence A. Rheins, PhD, DermTech International
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Keywords: biotechnology | cosmetics | deep sea | enzyme

Abstract: The use of protective enzymes in cosmetics has been resisted because of their well-known instability. However, we report here on heat- and UV-stable enzymes obtained from hydrothermal vents deep in the ocean.

The use of protective enzymes in cosmetics has been resisted because of their well-known instability. However, we report here on heat- and UV-stable enzymes obtained from hydrothermal vents deep in the ocean. In vitro and cell culture studies were carried out to test the potential for cosmetic applications. Catalase-like, SOD-like and glutathione peroxydase-like activities, all heat activated, were found to protect human skin fibroblasts, cell membrane lipids and collagen contraction capacity.