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Anti-aging Skin Care Benefits of Saccharina longicruris Extract
By: Alain Thibodeau, PhD, Innovacos Corp.
Posted: March 2, 2011, from the March 2011 issue of Cosmetics & Toiletries.
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- From Cosmetics & Toiletries
- March 2011 issue, pg 208
- 7 pages
- Saccharina longicruris
- cDNA array gene expression
- cellular senescence
- skin surface topography
- skin barrier function
- Adobe PDF for download
- Printed copies mailed to you
From $9 an article
Skin appearance and functionality are affected by a complex combination of factors including both genetic, i.e. intrinsic, and actinic, i.e. extrinsic or environmental. Indeed, genetic and actinic factors act together to modulate the expression of key genes involved in skin homeostasis. Intrinsic aging is genetically regulated and follows a chronological clock inside of cells, while environmental factors such as UV exposure, humidity and air pollutants are responsible for actinic aging. Together, genetic and actinic aging target important metabolic pathways in skin cells that trigger the signs of aging such as skin roughness and wrinkling.
At a molecular level, it has been demonstrated that collagen synthesis is reduced in aged skin cells and in cells damaged by UV radiation.1 Similarly, the expression of various matrix metalloproteases (MMPs), which cause the degradation of collagen fibers and other skin fibrillar components, is upregulated in aged cells as well as in cells exposed to UV, infrared radiation or excessive heat.2, 3 Furthermore, reactive oxygen species are molecular agents implicated in the deleterious effects of both intrinsic and extrinsic aging.1, 4
Lab Practical: S. longicruris
- This extract is a clear, yellowish solution that exhibits no specific odor.
- It typically comprises laminarans and fucoidans in equal amounts.
- Formulated in an aqueous base with 70% glycerin, the extract is soluble in water-based environments. It is also preservative-free.
- The extract should be added during cooling or at the end of the emulsion preparation.
This is only an excerpt of the full article that appeared in Cosmetics & Toiletries, but you can purchase the full-text version.