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New in Function (page 11 of 51)
Jun 30, 2011 | 10:29 AM CDT
Ingredient Profile—Salicylic Acid
By: Mike J. Fevola, Johnson & Johnson
2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.
Jun 01, 2011 | 01:36 PM CDT
Microchannel Processing: A Novel Approach to Making Emulsions
By: Mark Grace, Velocys Inc. and Larry Plonsker, C…
In the present article, microchannel emulsification is explored as a process method that precisely adds a dispersed phase into a continuous phase through an engineered dispersion plate. This approach is shown to produce emulsions with smaller droplets having tighter size distributions than conventional means, which leads to stable products with the limited need, if any, for surfactants.
Jun 01, 2011 | 01:31 PM CDT
The Effects of Solvents on Sunscreens: A New Ester to Improve Efficiency
By: Thomas O’Lenick, PhD, SurfaTech Corp.; and Den…
The present paper evaluates the effects of solvent systems on the in vivo SPFs of sunscreen formulations. Formulations incorporating identical active systems were prepared using traditional solvent systems and varying concentrations of sorbeth 2 hexaoleate, a new ester having both polar and nonpolar segments. Results indicate the ester enhances SPF in a dose-dependent manner.
Jun 01, 2011 | 01:26 PM CDT
Ingredient Profile: Titanium Dioxide
By: Mike J. Fevola, Johnson & Johnson
While TiO2 is often incorporated as a colorant and an opacifier in cosmetics and personal care products, its most important applications are as a sunscreen active and as a component of specialty pigments for color cosmetics.
May 02, 2011 | 01:46 PM CDT
Protection of Retinol in Organosilica Microparticles
By: Kim S. Finnie, PhD; and Chris Barbé, PhD, Cera…
In this article, retinol encapsulated in organosilica microparticles (12–14% w/w) having an average particle size of 0.3 micron are shown in a 40-day test period to exhibit enhanced stability to oxidation when compared with similar commercial stabilized retinol products.
May 02, 2011 | 01:35 PM CDT
Formula Troubleshooting—Preservation
By: Peter Tsolis and Steve Schnittger, The Estée L…
Cosmetics & Toiletries magazine is pleased to add this new “Formula Troubleshooting” column to the regular lineup. Led by column editor Peter Tsolis of The Estée Lauder Companies, it will cover some of the more common formulation challenges and suggest solutions for the benefit of novice formulators and as a refresher for seasoned experts.
May 02, 2011 | 01:29 PM CDT
Ingredient Profile—Polysorbate 20
By: Mike Fevola, Johnson & Johnson
Polyoxyethylene (20) sorbitan monolaurate (INCI: Polysorbate 20), is a ubiquitous nonionic surfactant employed in the formulation of countless cosmetic and personal care products.
Apr 06, 2011 | 10:49 AM CDT
A Review of Anti-irritants, Part II: Moisturizer, Anti-irritant Efficacy and Overall Interpretation*
By: Howard I. Maibach, MD, and Hongbo Zhai, MD, Un…
his column is the second of a two-part series about anti-irritants. Part I appeared in the March 2011 issue and covered anti-irritants, irritant reaction and barrier cream efficacy. The present column summarizes the efficacy of moisturizers and anti-irritant substances and provides an overall interpretation.
Apr 06, 2011 | 10:43 AM CDT
Formulating for Delivery From Elastomeric Nonwoven Substrates
By: Stacy A. Mundschau, Scott W. Wenzel and Barbar…
When developing moisturizers intended for application via nonwoven substrates, formulators must consider the hydrophobic oils, the affinity of those oils to the substrate, the add-on to the substrate and the stability of the compositions on the substrate. With these considerations, moisturizing formulations were developed and coated onto laminated substrates whose moisturization efficacies were evaluated as described here.
Apr 06, 2011 | 10:40 AM CDT
Nanoemulsions vs. Emulsions in the Delivery of Coenzyme Q10 and Tocopheryl Acetate
By: Thanaporn Amnuaikit, Wiwat Pichayakorn and Pra…
This article compares the ability of mixed emulsifier nanoemulsions and polysorbate 60 emulsions to deliver coenzyme Q10 and tocopheryl acetate into the skin. In vitro skin penetration data shows that in newborn pig skin, nanoemulsions can deliver higher amounts of both actives than emulsions.