Application/Category:
Need Training?
Build a solid foundation in science, formulation and product development—find out more!
Most Popular in:
Skin Care
New in Skin Care (page 8 of 22)
Jul 19, 2011 | 02:37 PM CDT
Properties of Emulsions: Structure and Skin Penetration
By: Th. Förster, B. Jackwerth, W. Pittermann, W. v…
This work studied the influence of emulsion type and structure on the penetration of vitamins as cosmetic active ingredients. An emulsion of the w/o type and two different o/w emulsions were compared with an oil solution as a standard. A systematic in vitro study of penetration into the stratum corneum and the living skin was performed with the isolated perfused bovide udder skin model. The results substantiate the influence of emulsion type and stucture on the degree of penetration of water-soluble and oil-soluble vitamins into the skin.
Jul 19, 2011 | 02:25 PM CDT
Cocamidopropyl Betaine
By: B. Grüning, PhD; D. Käseborn; and H.I. Leidrei…
This paper presents the methods for producing cocamidopropyl betaine (CAPB), an important secondary surfactant in cosmetic formulations, household cleaners, dishwashing agents and technical applications. With the widespread use of CAPB, more analytical methods to determine its contetns and byproducts are needed. The authors describe the current methods to determine CAPB purity and other characteristics.
Jun 30, 2011 | 11:35 AM CDT
Determining the Keratoltic Activities of Benzoyl Peroxide, Retinoic Acid and Salicylic Acid In vivo
By: Howard I. Maibach, MD, University of Californi…
Keratolysis is the separation or loosening of the stratum corneum (SC), and is part of the natural cycle of skin renewal and regeneration. Disordered keratolysis, resulting in skin overgrowth or excessive desquamation, is responsible for various skin disorders.
Jun 30, 2011 | 11:22 AM CDT
Bakuchiol in the Management of Acne-affected Skin
By: Ratan K. Chaudhuri, PhD, Sytheon Ltd. and Fran…
Bakuchiol, a meroterpene of plant origin, is shown here to act against four major pathophysiologic features that cause acne, suggesting its use to complement and/or enhance the effectiveness of current anti-acne agents. In addition, the material is non-irritating, presents no photo- or hydrolytic- stability issues and is easy to use.
Jun 30, 2011 | 10:29 AM CDT
Ingredient Profile—Salicylic Acid
By: Mike J. Fevola, Johnson & Johnson
2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.
Jun 01, 2011 | 01:36 PM CDT
Microchannel Processing: A Novel Approach to Making Emulsions
By: Mark Grace, Velocys Inc. and Larry Plonsker, C…
In the present article, microchannel emulsification is explored as a process method that precisely adds a dispersed phase into a continuous phase through an engineered dispersion plate. This approach is shown to produce emulsions with smaller droplets having tighter size distributions than conventional means, which leads to stable products with the limited need, if any, for surfactants.
May 02, 2011 | 01:41 PM CDT
Phytosphingosine: A Nature-inspired Sphingoid Base with Multiple Skin Benefits
By: Mike Farwick, Evonik-GoldSchmidt; and Anthony …
Phytosphingosine is an important component of ceramides that also exists as a free base in small quantities in the stratum corneum. Recently manufactured biotechnologically, it can act as an antimicrobial, anti-inflammatory, epidermal pro-differentiation mediator and an anti-acne compound, as this literature review shows. Through these activities, phytosphingosine is suggested as a skin-identical approach to skin care.
May 02, 2011 | 01:29 PM CDT
Ingredient Profile—Polysorbate 20
By: Mike Fevola, Johnson & Johnson
Polyoxyethylene (20) sorbitan monolaurate (INCI: Polysorbate 20), is a ubiquitous nonionic surfactant employed in the formulation of countless cosmetic and personal care products.
Apr 06, 2011 | 10:40 AM CDT
Nanoemulsions vs. Emulsions in the Delivery of Coenzyme Q10 and Tocopheryl Acetate
By: Thanaporn Amnuaikit, Wiwat Pichayakorn and Pra…
This article compares the ability of mixed emulsifier nanoemulsions and polysorbate 60 emulsions to deliver coenzyme Q10 and tocopheryl acetate into the skin. In vitro skin penetration data shows that in newborn pig skin, nanoemulsions can deliver higher amounts of both actives than emulsions.
Mar 02, 2011 | 03:42 PM CST
A Polyglucuronic Acid to Target the FIAF Adipokine for Slimming Effects
By: Laurent Rios, PhD; Cédric Delattre, PhD; Paola…
Effective slimming actives should reduce lipogenesis, increase lipolysis, promote fatty acid release and improve skin firmness. Here, the authors describe the development of such an active based on polyglucuronic acid. Further, this material is shown to act on a new biological pathway involving the fasting-induced adipose factor (FIAF) adipokine.