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Skin Care
New in Skin Care (page 8 of 21)
Jun 30, 2011 | 11:22 AM CDT
Bakuchiol in the Management of Acne-affected Skin
By: Ratan K. Chaudhuri, PhD, Sytheon Ltd. and Fran…
Bakuchiol, a meroterpene of plant origin, is shown here to act against four major pathophysiologic features that cause acne, suggesting its use to complement and/or enhance the effectiveness of current anti-acne agents. In addition, the material is non-irritating, presents no photo- or hydrolytic- stability issues and is easy to use.
Jun 30, 2011 | 10:29 AM CDT
Ingredient Profile—Salicylic Acid
By: Mike J. Fevola, Johnson & Johnson
2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.
Jun 01, 2011 | 01:36 PM CDT
Microchannel Processing: A Novel Approach to Making Emulsions
By: Mark Grace, Velocys Inc. and Larry Plonsker, C…
In the present article, microchannel emulsification is explored as a process method that precisely adds a dispersed phase into a continuous phase through an engineered dispersion plate. This approach is shown to produce emulsions with smaller droplets having tighter size distributions than conventional means, which leads to stable products with the limited need, if any, for surfactants.
May 02, 2011 | 01:41 PM CDT
Phytosphingosine: A Nature-inspired Sphingoid Base with Multiple Skin Benefits
By: Mike Farwick, Evonik-GoldSchmidt; and Anthony …
Phytosphingosine is an important component of ceramides that also exists as a free base in small quantities in the stratum corneum. Recently manufactured biotechnologically, it can act as an antimicrobial, anti-inflammatory, epidermal pro-differentiation mediator and an anti-acne compound, as this literature review shows. Through these activities, phytosphingosine is suggested as a skin-identical approach to skin care.
May 02, 2011 | 01:29 PM CDT
Ingredient Profile—Polysorbate 20
By: Mike Fevola, Johnson & Johnson
Polyoxyethylene (20) sorbitan monolaurate (INCI: Polysorbate 20), is a ubiquitous nonionic surfactant employed in the formulation of countless cosmetic and personal care products.
Apr 06, 2011 | 10:40 AM CDT
Nanoemulsions vs. Emulsions in the Delivery of Coenzyme Q10 and Tocopheryl Acetate
By: Thanaporn Amnuaikit, Wiwat Pichayakorn and Pra…
This article compares the ability of mixed emulsifier nanoemulsions and polysorbate 60 emulsions to deliver coenzyme Q10 and tocopheryl acetate into the skin. In vitro skin penetration data shows that in newborn pig skin, nanoemulsions can deliver higher amounts of both actives than emulsions.
Mar 02, 2011 | 03:42 PM CST
A Polyglucuronic Acid to Target the FIAF Adipokine for Slimming Effects
By: Laurent Rios, PhD; Cédric Delattre, PhD; Paola…
Effective slimming actives should reduce lipogenesis, increase lipolysis, promote fatty acid release and improve skin firmness. Here, the authors describe the development of such an active based on polyglucuronic acid. Further, this material is shown to act on a new biological pathway involving the fasting-induced adipose factor (FIAF) adipokine.
Feb 03, 2011 | 03:21 PM CST
Hyaluronic Acid Butyric Esters for the Improvement of Skin Functionality
By: Luigi Rigano and Chiara Andolfatto, Rigano Con…
The versatility of hyaluronic acid is connected to not only its size, but also to inherent opportunities within the molecule for multiple bonds and for the differentiated release of bound functional molecules. Here, ester bonds are used to introduce substitutes for the material’s alcohol groups, thus providing elasticizing, moisturizing and anti-aging benefits for skin care.
Jan 03, 2011 | 02:18 PM CST
Photostabilization of Retinol and Retinyl Palmitate by Ethylhexyl Methoxycrylene
By: Craig Bonda and Jean Zhang, The HallStar Compa…
This study examines the photostability of retinol and retinyl palmitate, finding they break down rapidly when exposed to UV radiation in the 290–400 nm range. This severely reduces their concentrations in finished formulations. However, when combined with ethylhexyl methoxycrylene, these retinoids are shown to be protected against photodegradation, thus preserving their concentrations both during the manufacturing process and following application to the skin.
Sep 29, 2010 | 10:36 AM CDT
Adapting Formulas to Skin Moisture Needs: A Review
By: Katerina Steventon, PhD, FaceWorkshops
Moisturization in skin care formulations requires an understanding of clinical needs, relevant biological targets and the aesthetic preferences of consumers. The efficacy of moisturizers must be established in vivo due to consumer interest in both visual and instrumental validation. This review outlines the challenges of formulating moisturizing facial skin care products in line with such principles.