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New in Antiaging (page 3 of 11)
Jun 01, 2011 | 02:37 PM CDT
By: Zoe Diana Draelos, MD, Dermatology Consulting …
The present article, adapted from Draelos and Pugliese*, provides a review of the chemistry involved in the glycation process to assist formulators in developing topical or nutricosmetic solutions for mature skin care.
May 02, 2011 | 01:46 PM CDT
By: Kim S. Finnie, PhD; and Chris Barbé, PhD, Cera…
In this article, retinol encapsulated in organosilica microparticles (12–14% w/w) having an average particle size of 0.3 micron are shown in a 40-day test period to exhibit enhanced stability to oxidation when compared with similar commercial stabilized retinol products.
Mar 02, 2011 | 03:49 PM CST
By: Alain Thibodeau, PhD, Innovacos Corp.
Aging triggers the modification of gene expression levels, negatively affecting skin’s ultrastructural integrity and resulting in dry, saggy skin and the appearance of wrinkles. However, an extract of Saccharina longicruris has been found to restore the expression levels of specific genes in senescent fibroblasts, in turn improving barrier function and hydration, increasing elasticity and reducing wrinkles, which are described in this article.
Nov 01, 2010 | 01:32 PM CDT
By: Estelle Loing, PhD, and Isabelle Lacasse, Unip…
Inspired by the roles of transforming growth factor-β and MITF in skin pigmentation, an active based on oligopeptide-68 was developed to influence these entities. In vitro, oligopeptide-68 is shown to abrogate the stimulatory effects of α-MSH on melanin pigment formation. In addition, clinical results demonstrate the peptide imparts significant and progressive whitening/lightening effects on skin.
Jul 30, 2010 | 02:45 PM CDT
By: Philippe Mondon, Nada André, Emmanuel Doridot,…
Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.
Apr 30, 2010 | 12:12 PM CDT
By: Celeste Hilling, Skin Authority
The medical community’s research toward the advancement of healing and tissue regeneration has identified Human Growth Factors (HGF) as critical components in cutaneous wound healing, suggesting their potential for skin cell rejuvenation. Here, the author reviews the present work in this area and proposes HGFs for skin regeneration and reparative products, providing an example.
Apr 30, 2010 | 12:09 PM CDT
By: Daniel Schmid, PhD, and Fred Zülli, PhD, Mibel…
Here, the authors describe mechanisms of stem cells and their potential for antiaging benefits. Cultures established from apple and grape varieties using a specialized culture technology revealed that aside from stimulating colony forming efficiency (CFE) and organogenic potential, the extracts improved the maintenance of epidermal stem cells. In addition, the grape extract provided UV protection.
Feb 26, 2010 | 11:22 AM CST
By: Eric Dupont, PhD, and Juan Gomez, Immanence; C…
As the mechanisms of skin aging become better understood, their complexity commands a different approach for antiaging benefits—i.e., integrating multiple complementary actives into a single formulation. In the present article, the authors describe a comprehensive formula designed to effectively address sixteen different mechanisms of skin aging.
Dec 30, 2009 | 02:59 PM CST
By: Bhaven Chavan, PhD, and Graham Pennick, Croda …
In the present article, the oral administration of echium oil is shown to increase collagen levels in the skin as well as barrier functioning and skin conductance. When applied topically, the oil increases dermal structural proteins, which results in a reduction in fine lines and wrinkles, and inhibits UV-induced inflammation.
Dec 30, 2009 | 02:24 PM CST
By: Helena Karajiannis, PhD, Dr. Helena Karajianni…
New research regarding the relationship between diet and skin and hair health has led to nutritional supplements developed for dermocosmetic and/or dermatological applications. However, obvious uncertainties exist in regard to the cosmetic capabilities of such preparations. This review provides an overview of existing data to examine the potential for nutritionals to treat skin and hair aging.