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New in Antiaging (page 3 of 11)
Sep 01, 2011 | 01:50 PM CDT
By: Giorgio Dell’Acqua, PhD, and Christian Wagner,…
Skin discoloration and excessive pigmentation due to increased melanin production is associated with skin inflammation and aging. Therefore, an extract rich in acetylated hydroxystilbenes from Rheum rhaponticum was combined with panthenyl triacetate to test in the melanogenesis pathway. The complex strongly reduced melanogenesis and melanin accumulation in human skin explants, decreased melanin content in pigmented spots, increased skin brightness and enhanced skin radiance on the face of human volunteers in a double-blind clinical study.
Sep 01, 2011 | 01:45 PM CDT
By: Marida Bimonte, Antonietta Carola, Annalisa Ti…
Coffea species have been widely evaluated for effects including oxidative stress protection and immunomodulation. The present study therefore evaluates the cosmetic activity of an extract obtained from cultured Coffea bengalensis stem cells. Results showed the extract imparted hydration activity in the keratinocytes, stimulated collagen synthesis in the fibroblasts and enhanced adipocyte differentiation starting from mesenchymal precursor cells.
Sep 01, 2011 | 01:39 PM CDT
By: Craig Bonda, Jean Zhang and Anna Pavlovic, The…
In this study, the effects of ultraviolet radiation (UVR) on trans-resveratrol were documented, finding that UV radiation causes it to undergo rapid and extensive photoisomerization and some photodecomposition. The antioxidant activity of trans-resveratrol is correspondingly reduced. However, in the presence of ethylhexyl methoxycrylene, a photostabilizer used in sunscreens, the effects of UV exposure on trans-resveratrol are minimized, thereby preserving its antioxidant activity and, presumably, its bioavailability.
Sep 01, 2011 | 01:34 PM CDT
By: Michael J. Fevola, PhD, Johnson & Johnson
L-Ascorbic acid (AscA), more commonly referred to as vitamin C, is best known for its vital role in human health and nutrition, where it functions as a cofactor in enzymatic reactions, such as collagen synthesis, and as an antioxidant.
Jun 01, 2011 | 02:37 PM CDT
By: Zoe Diana Draelos, MD, Dermatology Consulting …
The present article, adapted from Draelos and Pugliese*, provides a review of the chemistry involved in the glycation process to assist formulators in developing topical or nutricosmetic solutions for mature skin care.
May 02, 2011 | 01:46 PM CDT
By: Kim S. Finnie, PhD; and Chris Barbé, PhD, Cera…
In this article, retinol encapsulated in organosilica microparticles (12–14% w/w) having an average particle size of 0.3 micron are shown in a 40-day test period to exhibit enhanced stability to oxidation when compared with similar commercial stabilized retinol products.
Mar 02, 2011 | 03:49 PM CST
By: Alain Thibodeau, PhD, Innovacos Corp.
Aging triggers the modification of gene expression levels, negatively affecting skin’s ultrastructural integrity and resulting in dry, saggy skin and the appearance of wrinkles. However, an extract of Saccharina longicruris has been found to restore the expression levels of specific genes in senescent fibroblasts, in turn improving barrier function and hydration, increasing elasticity and reducing wrinkles, which are described in this article.
Nov 01, 2010 | 01:32 PM CDT
By: Estelle Loing, PhD, and Isabelle Lacasse, Unip…
Inspired by the roles of transforming growth factor-β and MITF in skin pigmentation, an active based on oligopeptide-68 was developed to influence these entities. In vitro, oligopeptide-68 is shown to abrogate the stimulatory effects of α-MSH on melanin pigment formation. In addition, clinical results demonstrate the peptide imparts significant and progressive whitening/lightening effects on skin.
Jul 30, 2010 | 02:45 PM CDT
By: Philippe Mondon, Nada André, Emmanuel Doridot,…
Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.
Apr 30, 2010 | 12:12 PM CDT
By: Celeste Hilling, Skin Authority
The medical community’s research toward the advancement of healing and tissue regeneration has identified Human Growth Factors (HGF) as critical components in cutaneous wound healing, suggesting their potential for skin cell rejuvenation. Here, the author reviews the present work in this area and proposes HGFs for skin regeneration and reparative products, providing an example.