Build a solid foundation in science, formulation and product development—find out more!
Most Popular in:
New in Antiaging (page 1 of 11)
Oct 08, 2013 | 11:48 AM CDT
By: Ilona Matejková, Pavel Klein, Martin Pravda, R…
A novel mechanism to increase collagen production based on improved hydroxylation of the collagen fiber is described here. In relation, the effects of a hydrophobic derivative of a-ketoglutarate on this mechanism are examined, and results indicate increases in collagen production in senescent fibroblasts in vitro. In vivo, a significant reduction in wrinkles and improvement in elasticity were observed.
Sep 03, 2013 | 02:26 PM CDT
By: Howard I. Maibach, MD; and Michal W.S. Ong
In recent years, new agents, especially from plants, have been discovered and extracted to test for their depigmenting effects in vitro and in vivo. This article reviews these most recent skin whitening agents of interest, whose efficacy, mechanism and safety have been tested.
Sep 03, 2013 | 01:01 PM CDT
By: Estelle Loing, PhD; Elisabeth Lamarque; Carine…
Ultraviolet and infrared exposure are sources of premature skin aging, characterized by solar elastosis and extracellular matrix degradation. Polygonum aviculare extract is a cathepsin G inhibitor, and is shown here to oppose photoaging and infra’aging by improving skin firmness and elasticity, in turn reducing the appearance of wrinkles.
May 31, 2013 | 11:36 AM CDT
Comparison of Age Determination by Three Evaluation Methods: Self-assessment, Expert Grader and Naïve Grader
By: Rosanna Mootoo, Nima Gohil, Cristina Stroever…
This exploratory study investigates how consumers perceive age, using objective and subjective approaches. Results of this study suggest that when a subjective approach is implemented for age determination, subjects affix their emotions to the evaluation. The reverse logic was applicable for the expert and naïve grader methods, as grader results appeared more neutral than the self-assessment.
May 06, 2013 | 01:17 PM CDT
By: Anthony J. Ribaudo, Textile Research Institute…
Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.
May 02, 2013 | 03:23 PM CDT
By: Charlene DeHaven, MD, Innovative Skincare
The purpose of this article is to discuss some key target molecules and receptors involved with aging mechanisms. As scientists learn more about the biochemical processes involved with aging, an increasing number of these loci are discovered that could be selected as targets for cosmeceutical ingredients with the final goal of an end-product with good anti-aging benefits.
Apr 02, 2013 | 08:57 AM CDT
By: Tania Milena Cortázar, Mauricio Guzmán Alonso …
Hesperomeles heterophylla Hook leaf extract was evaluated as described here for its application in anti-aging skin care. This traditional extract exhibited antioxidant and protective properties on the extracellular matrix due to high levels of polyphenols and flavonoids. Further, a formulation containing 0.35% extract was tested in vivo and showed promising effects on wrinkles and skin elasticity.
Apr 01, 2013 | 10:22 AM CDT
By: Giorgio Dell'Acqua, PhD
Sea-harvested brown algae is known to have skin benefits and previously has been associated with an increase in skin elasticity. Fucoidan, found in brown macroalgae such as Undaria pinnatifida, is a unique marine ingredient. It is a sulfated, fucose-rich polymer that in nature, protects the seaweed against a range of external stresses, including UV radiation and environmental contaminants such as marine-borne pathogens and viruses.
Mar 05, 2013 | 10:23 AM CST
By: Steven Isaacman, PhD, Nanometics LLC; Michael …
RNA interference (RNAi) is a gene-silencing technique that inhibits gene expression by causing the intracellular degradation of mRNA molecules. Since first reported in 1998, RNAi has sparked a revolution in molecular biology and has been employed in a myriad of biological contexts for the systematic evaluation of gene function.
Feb 01, 2013 | 02:28 PM CST
By: Luigi Rigano, PhD, Studio Rigano Industrial Co…
BB stands for “blemish balm” in Asia or “beauty balm” in some parts of Europe. It is defined loosely as a product that combines serum, moisturizer, base cream, foundation and sunscreen in one.