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Antiaging
New in Antiaging (page 1 of 11)
May 06, 2013 | 01:17 PM CDT
Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry
By: Anthony J. Ribaudo, Textile Research Institute…
Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.
May 02, 2013 | 03:23 PM CDT
Molecular Targets of Aging Processes
By: Charlene DeHaven, MD, Innovative Skincare
The purpose of this article is to discuss some key target molecules and receptors involved with aging mechanisms. As scientists learn more about the biochemical processes involved with aging, an increasing number of these loci are discovered that could be selected as targets for cosmeceutical ingredients with the final goal of an end-product with good anti-aging benefits.
Apr 02, 2013 | 08:57 AM CDT
Characterizing the Anti-aging Effects of Hesperomeles heterophylla Hook Leaf Extract
By: Tania Milena Cortázar, Mauricio Guzmán Alonso …
Hesperomeles heterophylla Hook leaf extract was evaluated as described here for its application in anti-aging skin care. This traditional extract exhibited antioxidant and protective properties on the extracellular matrix due to high levels of polyphenols and flavonoids. Further, a formulation containing 0.35% extract was tested in vivo and showed promising effects on wrinkles and skin elasticity.
Apr 01, 2013 | 10:22 AM CDT
Sustainable Ingredient Science: Brown Algae
By: Giorgio Dell'Acqua, PhD, Freedom Actives Corp.
Sea-harvested brown algae is known to have skin benefits and previously has been associated with an increase in skin elasticity. Fucoidan, found in brown macroalgae such as Undaria pinnatifida, is a unique marine ingredient. It is a sulfated, fucose-rich polymer that in nature, protects the seaweed against a range of external stresses, including UV radiation and environmental contaminants such as marine-borne pathogens and viruses.
Mar 05, 2013 | 10:23 AM CST
Technology Transfer—Silencing RNA for Cosmetic Effects
By: Steven Isaacman, PhD, Nanometics LLC; Michael …
RNA interference (RNAi) is a gene-silencing technique that inhibits gene expression by causing the intracellular degradation of mRNA molecules. Since first reported in 1998, RNAi has sparked a revolution in molecular biology and has been employed in a myriad of biological contexts for the systematic evaluation of gene function.
Feb 01, 2013 | 02:28 PM CST
Formula Anatomy Deciphered—BB Creams
By: Luigi Rigano, PhD, Studio Rigano Industrial Co…
BB stands for “blemish balm” in Asia or “beauty balm” in some parts of Europe. It is defined loosely as a product that combines serum, moisturizer, base cream, foundation and sunscreen in one.
Jan 04, 2013 | 12:43 PM CST
Consumer Perception of Fine Lines and Wrinkles Assessed by Qualitative Methods
By: Rosanna Mootoo, Stephanie Basile, Cristina St…
There are varying definitions, associations and overall impressions of fine lines and wrinkles among different consumer segments. The findings of this study offer invaluable insight into consumers’ opinions, and by qualitative in-depth interviews, they provide a well-defined vernacular for aging descriptors. This language is critical for developmental research, consumer evaluation and marketing within the cosmetic industry.
Dec 04, 2012 | 11:40 AM CST
A Compound to Increase Natural CoQ10 for Anti-aging Benefits
By: L. Bergeron; K. Cucumel, PhD; Y. Guerif; L. Mu…
Oxidative stress is a major factor in skin aging, thus a topical compound was designed to increase anti-oxidant coenzyme Q10 (CoQ10) within the body. Described here are in vivo and in vitro studies assessing the compound’s antioxidant and anti-aging capabilities. Results indicate that the modulation of intracellular CoQ10 and its binding proteins appears to protect skin from oxidative damage.
Oct 01, 2012 | 02:29 PM CDT
Clinical Evaluation of a Zinc- and Copper-based Eye Area Anti-aging Complex
By: Virginie Nollent, PharmD; Marion Lanctin; Ale…
A zinc and copper complex generating biomimetic electricity on a physiological level is shown here to improve the signs of photoaging in preclinical and clinical studies. This complex was applied to the eye area to confirm its efficacy as an anti-aging treatment option with good skin tolerance.
Sep 04, 2012 | 11:36 AM CDT
From Elastin to Elastic Fibers, Part II: The Clinical Effects of a Natural Dipeptide on the Biological Cascade
By: Philippe Mondon, Sebastian Fache and Emmanuel …
The peptide N-Acetyl-Tyr-Arg-Hexadecylester (NATAH), found in Part I to stimulate the production of elastic fibers in vitro, was next tested in vivo for its capacity to improve skin elasticity parameters, using various biophysical and imaging techniques. Significant differences in facial ptosis and extensibility were observed in the 56-day, vehicle-controlled clinical study described here.