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Comparatively Speaking: Azelaic Acid vs. Other Diacids
By: Anthony J. O'Lenick, Jr., Siltech LLC
Posted: January 26, 2010
page 2 of 2
Glutaric acid can be prepared by the ring-opening of butyrolactone. It is a common plasticizer and precursor to polyesters.
Adipic acid is produced from a mixture of cyclohexanol and cyclohexanone. Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs.
Pimelic acid has been synthesized from cyclohexanone and from salicylic acid. Derivatives of pimelic acid are involved in the biosynthesis of lysine.
Sebacic acid is a naturally occurring acid, but it is derived commercially from castor oil, mostly in China. Sebacic acid is used in plasticizers, lubricants and hydraulic fluids. Sebacic acid is also used as an intermediate for aromatics, antiseptics and painting materials.