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Skin Lightening Gel
Posted: September 8, 2006
Company: Pentapharm Inc. (Centerchem Inc.)
|Hydroxyethylcellulose (Natrosol 250 HHR, Hercules F)||1.50|
|PEG/PPG-20/6 dimethicone (Abil B 88183, Degussa/Goldschmidt)||2.00|
|Sodium hydroxide, 10%||qs to pH 8.5|
|Citric Acid||qs to pH 4.0-5.0|
|Ethoxydiglycol (EDG Plus ,Moelhausen S.p.A.)||5.00|
|Alpha-Arbutin (Alpha-Arbutin, Pentapharm)||1.00|
|Benzophenone-9 (Uvinul DS 49, BASF)||0.20|
Procedure: For A, disperse hydroxyethylcellulose in water, then add PEG/PPG-20/6 dimethicone. Mix B, then add it to A. Adjust the pH to approx. 8.5 with NaOH 10% (of C) to obtain a clear gel. Then adjust the pH to approx. 4.0-5.0 with citric acid (also of C). Add D under stirring. Add E and mix to obtain a homogeneous gel.