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Oct 05, 2011 | 11:49 AM CDT
Antioxidants in Sunscreens for Improved ROS Protection
By: Kerry Hanson and Christoper Bardeen, Universit…
In the present article, sunscreens containing the antioxidants vitamin E and diethylhexyl syringylidene malonate were tested for their efficacy in preventing UV-induced reactive oxygen species in the lower stratum corneum. The addition of the antioxidants was found to significantly improve the ability of low to high SPF sunscreens to attenuate ROS formation in UV-exposed skin.
Oct 05, 2011 | 11:40 AM CDT
Ingredient Profile—Carbomer
By: Mike J. Fevola, Johnson & Johnson
Carbomers, a family of crosslinked acrylic acid polymers, are essential ingredients in numerous products, including: pharmaceuticals; cosmetics and personal care items; household, industrial and institutional care products; printing inks; adhesives and coatings. This column will explore the chemistry and properties of carbomers that have earned them this well-deserved reputation.
Oct 05, 2011 | 11:37 AM CDT
Formula Anatomy Deciphered— Anti-acne Ingredients
By: Eric S. Abrutyn, TPC2 Advisors Ltd.
Acne vulgaris (acne) is a skin disease that can be caused by multiple chronic issues including: hyperkeratinization, sebaceous gland hyperplasia with seborrhea, Propionibacterium acnes proliferation and inflammation.
Sep 08, 2011 | 03:19 PM CDT
Dry Skin: Moisturizing and Emolliency
By: Bernard Idson, PhD, College of Pharmacy, The U…
Youthful skin is perceived as moist (or at least nondry), clean soft and virtually free of wrinkles. As consumers advance in age, concern about dry skin increases, and simply washing with soap and water gives way to us of products designed to treat the symptom, which all end up bearing some version of a moisturizer.
Sep 01, 2011 | 01:50 PM CDT
Lightening and Illuminating Skin With Acetylated Hydroxystilbenes From Rheum rhaponticum
By: Giorgio Dell’Acqua, PhD, and Christian Wagner,…
Skin discoloration and excessive pigmentation due to increased melanin production is associated with skin inflammation and aging. Therefore, an extract rich in acetylated hydroxystilbenes from Rheum rhaponticum was combined with panthenyl triacetate to test in the melanogenesis pathway. The complex strongly reduced melanogenesis and melanin accumulation in human skin explants, decreased melanin content in pigmented spots, increased skin brightness and enhanced skin radiance on the face of human volunteers in a double-blind clinical study.
Sep 01, 2011 | 01:45 PM CDT
Coffea bengalensis for Antiwrinkle and Skin Toning Applications
By: Marida Bimonte, Antonietta Carola, Annalisa Ti…
Coffea species have been widely evaluated for effects including oxidative stress protection and immunomodulation. The present study therefore evaluates the cosmetic activity of an extract obtained from cultured Coffea bengalensis stem cells. Results showed the extract imparted hydration activity in the keratinocytes, stimulated collagen synthesis in the fibroblasts and enhanced adipocyte differentiation starting from mesenchymal precursor cells.
Sep 01, 2011 | 01:39 PM CDT
The Photostability and Photostabilization of trans-Resveratrol
By: Craig Bonda, Jean Zhang and Anna Pavlovic, The…
In this study, the effects of ultraviolet radiation (UVR) on trans-resveratrol were documented, finding that UV radiation causes it to undergo rapid and extensive photoisomerization and some photodecomposition. The antioxidant activity of trans-resveratrol is correspondingly reduced. However, in the presence of ethylhexyl methoxycrylene, a photostabilizer used in sunscreens, the effects of UV exposure on trans-resveratrol are minimized, thereby preserving its antioxidant activity and, presumably, its bioavailability.
Sep 01, 2011 | 01:34 PM CDT
Ingredient Profile—Ascorbic Acid
By: Michael J. Fevola, PhD, Johnson & Johnson
L-Ascorbic acid (AscA), more commonly referred to as vitamin C, is best known for its vital role in human health and nutrition, where it functions as a cofactor in enzymatic reactions, such as collagen synthesis, and as an antioxidant.
Sep 01, 2011 | 01:30 PM CDT
Formula Anatomy Deciphered—Skin Lighteners
By: Eric S. Abrutyn, TPC2 Advisors Ltd.
The term “skin lightening” has been positioned in the cosmetic market to denote the return of skin’s color to a more natural transparent tone, providing a more even skin tone and lighter skin pigment. Topical skin lighteners suppress production of melanin pigment, prevent darkening of the skin or modify pigmentation such as blotches and freckles.
Aug 01, 2011 | 02:12 PM CDT
Evaluating Hair Conditioning with Instrumental Combing
By: Trefor Evans, PhD, TRI/Princeton
When formulating a hair care product, there is often a need for testing that validates the product’s technical performance. This testing provides guidance to create formulas with appropriate performance, while also communicating the product’s message to the consumer. This article discusses the use of instrumental combing measurements when formulating hair conditioning products.