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New in Formulating (page 5 of 66)
Nov 01, 2012 | 12:43 PM CDT
Ingredient Profile—Sorbic Acid/Potassium Sorbate
By: Michael J. Fevola, PhD, Johnson & Johnson
SorbH and KSorb have become increasingly popular options for cosmetic preservatives due to their worldwide status as Generally Recognized As Safe (GRAS) food ingredients and their long and successful use history.
Oct 01, 2012 | 02:37 PM CDT
Inducing Hormesis for a Lipofilling-like Action
By: Carine Bézivin, PhD, Lucas Meyer Cosmetics
The present article discusses a new approach to mimic lipofilling—the activation of hormesis, which is accomplished by the described encapsulated active designed to induce a transitory stress and initiate an overcompensation to reestablish homeostasis. This leads to the compensation of age-induced lipoatrophy and correction of wrinkles and folds, for a younger-looking appearance.
Oct 01, 2012 | 02:29 PM CDT
Clinical Evaluation of a Zinc- and Copper-based Eye Area Anti-aging Complex
By: Virginie Nollent, PharmD; Marion Lanctin; Ale…
A zinc and copper complex generating biomimetic electricity on a physiological level is shown here to improve the signs of photoaging in preclinical and clinical studies. This complex was applied to the eye area to confirm its efficacy as an anti-aging treatment option with good skin tolerance.
Oct 01, 2012 | 02:11 PM CDT
Designing Mild Personal Care Products: A Case Study
By: Paul Cornwell, PhD, and Jeremy Goodwin, PhD, Z…
This article reviews the mechanisms underlying skin irritation and sensitization, and methods used in a case study to test cosmetic products for their potential to cause irritation. It also covers the main skin conditions that can influence susceptibility to irritation, as well as ingredients affecting the mildness of cosmetic products.
Oct 01, 2012 | 02:06 PM CDT
Formula Troubleshooting—Anhydrous Product Instability
By: Peter Tsolis, The Estée Lauder Companies; and …
Many anhydrous products are mixtures of oils, esters, fatty alcohols, waxes, preservatives, fragrances and various pigments. Combining these materials is a complex undertaking, and varying the concentration even slightly changes the dynamics and aesthetics of the final product; in the worst cases, it causes instability.
Sep 27, 2012 | 03:28 PM CDT
Cationic Guar Gum
By: Mark S. Freeland, Iris Holder and Jeanette Tuc…
Guar is a natural water soluble polymer principally grown in the Asian subcontinent, specifically India and Pakistan. Also, guar gum is a crop studied in agronomy programs in the United States and many other parts of the world.
Sep 04, 2012 | 11:36 AM CDT
From Elastin to Elastic Fibers, Part II: The Clinical Effects of a Natural Dipeptide on the Biological Cascade
By: Philippe Mondon, Sebastian Fache and Emmanuel …
The peptide N-Acetyl-Tyr-Arg-Hexadecylester (NATAH), found in Part I to stimulate the production of elastic fibers in vitro, was next tested in vivo for its capacity to improve skin elasticity parameters, using various biophysical and imaging techniques. Significant differences in facial ptosis and extensibility were observed in the 56-day, vehicle-controlled clinical study described here.
Sep 04, 2012 | 11:31 AM CDT
Saccharide Isomerate to Deeply Hydrate Skin and Scalp
By: Jochen Klock, PhD, and Volker Rosenberger, PhD…
Saccharide isomerate, designed to closely resemble a carbohydrate complex found in human stratum corneum, is shown here to provide up to 72 hr of deep hydration to skin and, for the first time, rinse-off soothing to the scalp. Its unique binding mechanism to skin and scalp create new opportunities for leave-on and rinse-off products.
Sep 04, 2012 | 11:25 AM CDT
Formula Anatomy Deciphered—Sensory in Cosmetics
By: Luigi Rigano, PhD, Studio Rigano Industrial Co…
The sensory world is fueled by research conducted in different disciplines such as biology, neurobiology and sense chemistry. It extends to many industrial sectors where perception elements are crucial, including cosmetics.
Sep 04, 2012 | 11:20 AM CDT
Formulating with Naturals—Sun Care
By: Art Georgalas, Georgalas Endeavors
The industry continues to seek protection from the sun without chemical reactions on the skin, in the body or in the environment.