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New in Formulating (page 14 of 66)
Jun 30, 2011 | 10:29 AM CDT
Ingredient Profile—Salicylic Acid
By: Mike J. Fevola, Johnson & Johnson
2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.
Jun 01, 2011 | 02:37 PM CDT
Glycation and Skin Aging: A Review
By: Zoe Diana Draelos, MD, Dermatology Consulting …
The present article, adapted from Draelos and Pugliese*, provides a review of the chemistry involved in the glycation process to assist formulators in developing topical or nutricosmetic solutions for mature skin care.
Jun 01, 2011 | 01:36 PM CDT
Microchannel Processing: A Novel Approach to Making Emulsions
By: Mark Grace, Velocys Inc. and Larry Plonsker, C…
In the present article, microchannel emulsification is explored as a process method that precisely adds a dispersed phase into a continuous phase through an engineered dispersion plate. This approach is shown to produce emulsions with smaller droplets having tighter size distributions than conventional means, which leads to stable products with the limited need, if any, for surfactants.
Jun 01, 2011 | 01:31 PM CDT
The Effects of Solvents on Sunscreens: A New Ester to Improve Efficiency
By: Thomas O’Lenick, PhD, SurfaTech Corp.; and Den…
The present paper evaluates the effects of solvent systems on the in vivo SPFs of sunscreen formulations. Formulations incorporating identical active systems were prepared using traditional solvent systems and varying concentrations of sorbeth 2 hexaoleate, a new ester having both polar and nonpolar segments. Results indicate the ester enhances SPF in a dose-dependent manner.
Jun 01, 2011 | 01:26 PM CDT
Ingredient Profile: Titanium Dioxide
By: Mike J. Fevola, Johnson & Johnson
While TiO2 is often incorporated as a colorant and an opacifier in cosmetics and personal care products, its most important applications are as a sunscreen active and as a component of specialty pigments for color cosmetics.
May 02, 2011 | 01:50 PM CDT
A Review of Nail Polish: The Industrial Cosmetic
By: Frank C. Pagano, PhD, Chanel Inc.
In the present article, nail polish is reviewed for its function as a decorative coating for the nails. In addition, formulation requirements are described to assist nail polish developers in achieving both the desired decorative effects as well as the necessary performance as a coating.
May 02, 2011 | 01:46 PM CDT
Protection of Retinol in Organosilica Microparticles
By: Kim S. Finnie, PhD; and Chris Barbé, PhD, Cera…
In this article, retinol encapsulated in organosilica microparticles (12–14% w/w) having an average particle size of 0.3 micron are shown in a 40-day test period to exhibit enhanced stability to oxidation when compared with similar commercial stabilized retinol products.
May 02, 2011 | 01:41 PM CDT
Phytosphingosine: A Nature-inspired Sphingoid Base with Multiple Skin Benefits
By: Mike Farwick, Evonik-GoldSchmidt; and Anthony …
Phytosphingosine is an important component of ceramides that also exists as a free base in small quantities in the stratum corneum. Recently manufactured biotechnologically, it can act as an antimicrobial, anti-inflammatory, epidermal pro-differentiation mediator and an anti-acne compound, as this literature review shows. Through these activities, phytosphingosine is suggested as a skin-identical approach to skin care.
May 02, 2011 | 01:35 PM CDT
Formula Troubleshooting—Preservation
By: Peter Tsolis and Steve Schnittger, The Estée L…
Cosmetics & Toiletries magazine is pleased to add this new “Formula Troubleshooting” column to the regular lineup. Led by column editor Peter Tsolis of The Estée Lauder Companies, it will cover some of the more common formulation challenges and suggest solutions for the benefit of novice formulators and as a refresher for seasoned experts.
May 02, 2011 | 01:29 PM CDT
Ingredient Profile—Polysorbate 20
By: Mike Fevola, Johnson & Johnson
Polyoxyethylene (20) sorbitan monolaurate (INCI: Polysorbate 20), is a ubiquitous nonionic surfactant employed in the formulation of countless cosmetic and personal care products.