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Jul 19, 2011 | 02:37 PM CDT
Properties of Emulsions: Structure and Skin Penetration
By: Th. Förster, B. Jackwerth, W. Pittermann, W. v…
This work studied the influence of emulsion type and structure on the penetration of vitamins as cosmetic active ingredients. An emulsion of the w/o type and two different o/w emulsions were compared with an oil solution as a standard. A systematic in vitro study of penetration into the stratum corneum and the living skin was performed with the isolated perfused bovide udder skin model. The results substantiate the influence of emulsion type and stucture on the degree of penetration of water-soluble and oil-soluble vitamins into the skin.
Jul 19, 2011 | 02:25 PM CDT
Cocamidopropyl Betaine
By: B. Grüning, PhD; D. Käseborn; and H.I. Leidrei…
This paper presents the methods for producing cocamidopropyl betaine (CAPB), an important secondary surfactant in cosmetic formulations, household cleaners, dishwashing agents and technical applications. With the widespread use of CAPB, more analytical methods to determine its contetns and byproducts are needed. The authors describe the current methods to determine CAPB purity and other characteristics.
Jun 30, 2011 | 11:35 AM CDT
Determining the Keratoltic Activities of Benzoyl Peroxide, Retinoic Acid and Salicylic Acid In vivo
By: Howard I. Maibach, MD, University of Californi…
Keratolysis is the separation or loosening of the stratum corneum (SC), and is part of the natural cycle of skin renewal and regeneration. Disordered keratolysis, resulting in skin overgrowth or excessive desquamation, is responsible for various skin disorders.
Jun 30, 2011 | 11:22 AM CDT
Bakuchiol in the Management of Acne-affected Skin
By: Ratan K. Chaudhuri, PhD, Sytheon Ltd. and Fran…
Bakuchiol, a meroterpene of plant origin, is shown here to act against four major pathophysiologic features that cause acne, suggesting its use to complement and/or enhance the effectiveness of current anti-acne agents. In addition, the material is non-irritating, presents no photo- or hydrolytic- stability issues and is easy to use.
Jun 30, 2011 | 11:12 AM CDT
Formula Anatomy Deciphered—Baby Care
By: Eric S. Abrutyn, TPC2 Advisors Ltd.
The baby care segment of the personal care market offers a limited variety of products that are mostly focused on cleansing and moisturization.
Jun 30, 2011 | 10:29 AM CDT
Ingredient Profile—Salicylic Acid
By: Mike J. Fevola, Johnson & Johnson
2-Hydroxybenzoic acid, or salicylic acid (SA), is among the most important medicinal compounds ever discovered. Since ancient times, humans have benefited from the therapeutic effects of naturally occurring SA precursors, which readily metabolize to SA and provide analgesic, anti- inflammatory and antipyretic benefits.
Jun 01, 2011 | 02:37 PM CDT
Glycation and Skin Aging: A Review
By: Zoe Diana Draelos, MD, Dermatology Consulting …
The present article, adapted from Draelos and Pugliese*, provides a review of the chemistry involved in the glycation process to assist formulators in developing topical or nutricosmetic solutions for mature skin care.
Jun 01, 2011 | 01:36 PM CDT
Microchannel Processing: A Novel Approach to Making Emulsions
By: Mark Grace, Velocys Inc. and Larry Plonsker, C…
In the present article, microchannel emulsification is explored as a process method that precisely adds a dispersed phase into a continuous phase through an engineered dispersion plate. This approach is shown to produce emulsions with smaller droplets having tighter size distributions than conventional means, which leads to stable products with the limited need, if any, for surfactants.
Jun 01, 2011 | 01:31 PM CDT
The Effects of Solvents on Sunscreens: A New Ester to Improve Efficiency
By: Thomas O’Lenick, PhD, SurfaTech Corp.; and Den…
The present paper evaluates the effects of solvent systems on the in vivo SPFs of sunscreen formulations. Formulations incorporating identical active systems were prepared using traditional solvent systems and varying concentrations of sorbeth 2 hexaoleate, a new ester having both polar and nonpolar segments. Results indicate the ester enhances SPF in a dose-dependent manner.
Jun 01, 2011 | 01:26 PM CDT
Ingredient Profile: Titanium Dioxide
By: Mike J. Fevola, Johnson & Johnson
While TiO2 is often incorporated as a colorant and an opacifier in cosmetics and personal care products, its most important applications are as a sunscreen active and as a component of specialty pigments for color cosmetics.